Ethyl 2-amino-4-(2-fluoro-5-methoxyphenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carboxylate CAS 445266-56-8
| CAS No. | 445266-56-8 |
| Molecular Formula | C21H24FNO5 |
| Molecular Weight | 389.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ethyl 2-amino-4-(2-fluoro-5-methoxyphenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carboxylate is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Ethyl 2-amino-4-(2-fluoro-5-methoxyphenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carboxylate (CAS 445266-56-8), a certified reference material (molecular formula C21H24FNO5, MW 389.42 g/mol) for analytical method development and quality control.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Ethyl 2-amino-4-(2-fluoro-5-methoxyphenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carboxylate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 389.42 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Ethyl 2-amino-4-(2-fluoro-5-methoxyphenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H24FNO5 |
| Molecular Weight | 389.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
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Recommended Standards
- 4-Fluoro-N-(3-(((4-fluorobenzyl)oxy)methyl)phenyl)benzenesulfonamide (CAS 338392-93-1)
- N-methyl-2-(3-((3-(trifluoromethyl)benzyl)oxy)thiophene-2-carbonyl)hydrazine-1-carbothioamide (CAS 343376-09-0)
- 3-[3-(2,3-Dihydro-indole-1-sulfonyl)-4,5-dimethoxy-phenyl]-acrylic acid (CAS 326907-81-7)
- Ezetimibe Impurity 63 (CAS CATO-C4X-109863)
- (S)-2-Amino-N-(1-hydroxy-3-methylbutan-2-yl)-3-methoxybenzamide (CAS 1786556-76-0)
- (5,7-Dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)methanol (CAS 54535-00-1)
- 5-Cyclopropyl-1-ethyl-4-iodo-1H-pyrazole (CAS 1458615-94-5)
- 3,4-dimethylpyrrolidine hydrochloride (CAS 742100-61-4)
- tert-Butyl 4-(5-bromo-2-fluorobenzoyl)piperidine-1-carboxylate (CAS 1228631-72-8)
- Bortezomib Impurity 17 (CAS 1194235-41-0)
- 6-Bromo-5-chloro-1,2,3,4-tetrahydroquinolin-2-one (CAS 1404367-63-0)
- 1-[(4-Fluoro-phenylcarbamoyl)-methyl]-2-oxo-1,2-dihydro-pyridine-3-carboxylic acid (CAS 1171917-13-7)
- Diethyl 2-(tetrahydrofuran-3-yl)malonate (CAS 949885-88-5)
- Semaglutide impurity 29 (CAS CATO-C4X-222629)
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