Bortezomib Impurity 17 CAS 1194235-41-0
| CAS No. | 1194235-41-0 |
| Molecular Formula | C28H34BN5O5 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Bortezomib Impurity 17 (CAS 1194235-41-0), a pharmacopoeial impurity reference standard (molecular formula C28H34BN5O5, MW 531.42 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Bortezomib Impurity 17 (C28H34BN5O5) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 14.5, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 531.42 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C28H34BN5O5 |
| Molecular Weight | 531.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 5 |
Related Bortezomib Standards
- Bortezomib Impurity 77 (CAS 103435-88-7)
- Bortezomib Impurity 36 (CAS 1093959-75-1)
- Bortezomib Impurity 35 (CAS 1104011-35-9)
- Bortezomib Impurity 45 (CAS 110755-29-8)
- Bortezomib Impurity 6 (CAS 1132709-14-8)
- Bortezomib Impurity 7 (CAS 1132709-15-9)
- Bortezomib Impurity 5 (CAS 1132709-16-0)
- Bortezomib Impurity 2 (CAS 114457-94-2)
Recommended Standards
- Furosemide Impurity 45 (CAS CATO-C4X-140245)
- Suzetrigine Impurity 13 (CAS CATO-C4X-336913)
- Vonoprazan Impurity 209 (CAS 31543-47-2)
- Tamsulosin Impurity 15 (CAS 3251-30-7)
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