N-[1-(Adamantan-1-yl)ethyl]-3-amino-6-ethyl-5H,6H,7H,8H-thieno[2,3-b]quinoline-2-carboxamide CAS 445269-04-5
| CAS No. | 445269-04-5 |
| Molecular Formula | C26H35N3OS |
| Molecular Weight | 437.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 437.64 g/mol gives N-[1-(Adamantan-1-yl)ethyl]-3-amino-6-ethyl-5H,6H,7H,8H-thieno[2,3-b]quinoline-2-carboxamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
N-[1-(Adamantan-1-yl)ethyl]-3-amino-6-ethyl-5H,6H,7H,8H-thieno[2,3-b]quinoline-2-carboxamide (CAS 445269-04-5), molecular formula C26H35N3OS and molecular weight 437.64 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N-[1-(Adamantan-1-yl)ethyl]-3-amino-6-ethyl-5H,6H,7H,8H-thieno[2,3-b]quinoline-2-carboxamide (C26H35N3OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-[1-(Adamantan-1-yl)ethyl]-3-amino-6-ethyl-5H,6H,7H,8H-thieno[2,3-b]quinoline-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H35N3OS |
| Molecular Weight | 437.64 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related N Standards
- 2-((6-(Adamantan-1-yl)-3-cyanopyridin-2-yl)thio)-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide (CAS 329935-52-6)
- 2-((6-(Adamantan-1-yl)-3-cyano-4-(trifluoromethyl)pyridin-2-yl)thio)-N-cyclopropylacetamide (CAS 488708-78-7)
- 6-(Adamantan-1-yl)-3-amino-N-cyclopropyl-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 489405-10-9)
- N-(Adamantan-1-yl)-2-{[3-cyano-4-(trifluoromethyl)-5H,6H,7H-cyclopenta[b]pyridin-2-yl]sulfanyl}acetamide (CAS 626222-15-9)
- N-(adamantan-1-yl)-3-amino-4-(trifluoromethyl)-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide (CAS 664999-36-4)
- n-(Adamantan-1-yl)-2-((3-(3-hydroxypropyl)-4-oxo-3,4-dihydroquinazolin-2-yl)thio)propanamide (CAS 1007763-39-4)
- 1-(Adamantan-1-yl)-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)urea (CAS 548748-67-0)
- (2-(Adamantan-1-yl)-6,8-dichloroquinolin-4-yl)(piperidin-2-yl)methanol (CAS 785718-37-8)
Recommended Standards
- 4-Chloro-3-[(4-iodophenyl)sulfamoyl]benzoic acid (CAS 379725-42-5)
- (3AS,3bS,4aS,5R,5aR)-5-(((tert-butyldiphenylsilyl)oxy)methyl)-2,2-dimethyltetrahydrocyclopropa[3,4]cyclopenta[1,2-d][1,3]dioxol-3b(3aH)-amine (CAS 1069040-54-5)
- 2-Chloro-5-(n-(4-iodophenyl)sulfamoyl)benzoic acid (CAS 380432-24-6)
- SP 100030 (CAS 154563-54-9)
- 2,2,2-Trifluoro-1-(isoquinolin-1-yl)ethan-1-one (CAS 1196157-18-2)
- 1,8-Diamino-6-ethoxy-3-morpholino-2,7-naphthyridine-4-carbonitrile (CAS 459153-40-3)
- Butyl(3-phenylbutyl)amine hydrochloride (CAS 1240581-91-2)
- 3-Chloro-2-fluoro-5-(trifluoromethyl)benzylamine (CAS 261763-07-9)
- Ethyl 4,6-dimethylpyrimidine-5-carboxylate (CAS 305794-79-0)
- 4-O-(2-Acetamido-2-deoxy-b-D-glucopyranosyl)ribitol (CAS 21150-24-3)
- 5,7-Dichloro-2-(difluoromethyl)-8-fluoropyrido[4,3-d]pyrimidin-4(3H)-one (CAS 2763159-69-7)
- 2-(4-((Benzyl(isopropyl)amino)methyl)piperidin-1-yl)ethanol (CAS 1353975-19-5)
- 7-Chloro-1H-indole-6-carboxylic acid (CAS 1055320-72-3)
- Neuropeptide Y (2-36), amide, porcine (CAS 102961-52-4)
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