2-((6-(Adamantan-1-yl)-3-cyano-4-(trifluoromethyl)pyridin-2-yl)thio)-N-cyclopropylacetamide CAS 488708-78-7
| CAS No. | 488708-78-7 |
| Molecular Formula | C22H24F3N3OS |
| Molecular Weight | 435.51 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-((6-(Adamantan-1-yl)-3-cyano-4-(trifluoromethyl)pyridin-2-yl)thio)-N-cyclopropylacetamide is closely related to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-((6-(Adamantan-1-yl)-3-cyano-4-(trifluoromethyl)pyridin-2-yl)thio)-N-cyclopropylacetamide (CAS 488708-78-7), a certified reference material (molecular formula C22H24F3N3OS, MW 435.51 g/mol) for analytical method development and quality control.
2-((6-(Adamantan-1-yl)-3-cyano-4-(trifluoromethyl)pyridin-2-yl)thio)-N-cyclopropylacetamide (C22H24F3N3OS) contains a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H24F3N3OS |
| Molecular Weight | 435.51 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Adamantan Standards
- 6-(Adamantan-1-yl)-3-amino-N-cyclopropyl-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 489405-10-9)
- N-(Adamantan-1-yl)-2-{[3-cyano-4-(trifluoromethyl)-5H,6H,7H-cyclopenta[b]pyridin-2-yl]sulfanyl}acetamide (CAS 626222-15-9)
- N-(adamantan-1-yl)-3-amino-4-(trifluoromethyl)-6,7-dihydro-5H-cyclopenta[b]thieno[3,2-e]pyridine-2-carboxamide (CAS 664999-36-4)
- N-[1-(Adamantan-1-yl)ethyl]-3-amino-6-ethyl-5H,6H,7H,8H-thieno[2,3-b]quinoline-2-carboxamide (CAS 445269-04-5)
- 2-((6-(Adamantan-1-yl)-3-cyanopyridin-2-yl)thio)-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide (CAS 329935-52-6)
- n-(Adamantan-1-yl)-2-((3-(3-hydroxypropyl)-4-oxo-3,4-dihydroquinazolin-2-yl)thio)propanamide (CAS 1007763-39-4)
- 1-(Adamantan-1-yl)-3-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)urea (CAS 548748-67-0)
- 2-(Adamantan-1-ylamino)-N-(2-chloro-5-(N,N-dimethylsulfamoyl)phenyl)acetamide (CAS 852902-81-9)
Recommended Standards
- 8-tert-Butyl-4-(3,4,5-trimethoxybenzoyl)-1-oxa-4-azaspiro[4.5]decane-3-carboxylic acid (CAS 1326809-77-1)
- 4-(4-(Allyloxy)benzoyl)-3-hydroxy-5-(4-isopropylphenyl)-1-(2-methoxyethyl)-1H-pyrrol-2(5H)-one (CAS 618077-36-4)
- Benzyl 2-[[(2S)-2-[[2-(tert-Butoxycarbonylamino)acetyl]amino]-4-methyl-pentanoyl]amino]acetate (CAS 118700-52-0)
- 4-Hydroxy-3-[[2-(4-tricyclo[3.3.1.13,7]dec-1-ylphenoxy)acetyl]amino]-benzoic Acid Methyl Ester (CAS 934593-90-5)
- 6-((5-Formylquinolin-8-yl)oxy)nicotinonitrile (CAS 1087351-67-4)
- 2-Phenylthiazol-4(5H)-one (CAS 827-46-3)
- 3-(Hydroxymethyl)piperidin-3-ol (CAS 848069-91-0)
- 3-Bromo-5-fluoro-2-isopropoxyaniline (CAS 1096834-81-9)
- N-Ethyl-2-oxo-1,2-dihydropyridine-3-sulfonamide (CAS 1774901-78-8)
- Ethyl 4-(3,3-dimethylureido)benzoate (CAS 92789-05-4)
- [5-(4-Methanesulfonylphenyl)-2-methyl-1-[3-(trifluoromethyl)phenyl]-1H-pyrrol-3-yl]methyl 3-methylbenzoate (CAS 338749-55-6)
- (E)-3-cyclopropyl-3-(3,4-dimethoxyphenyl)acrylic acid (CAS 1017140-29-2)
- 1-(3-(Difluoromethyl)-2-fluorophenyl)ethan-1-amine (CAS 1391195-60-0)
- (Tyr?)-C-Peptide (dog) (CAS 101135-67-5)
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