4-Fluoro-3-trifluoromethylbenzeneboronic acid pinacol ester, 97% CAS 445303-14-0
| CAS No. | 445303-14-0 |
| Molecular Formula | C7H5BF4O2 |
| Molecular Weight | 207.92 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4-Fluoro-3-trifluoromethylbenzeneboronic acid pinacol ester, 97% (CAS 445303-14-0), a certified reference material (molecular formula C7H5BF4O2, MW 207.92 g/mol) for analytical method development and quality control.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, 4-Fluoro-3-trifluoromethylbenzeneboronic acid pinacol ester, 97% is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 207.92 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H5BF4O2 |
| Molecular Weight | 207.92 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
Related Fluoro Standards
- 2-Fluoro-3-(trifluoromethyl)phenylboronic Acid (CAS 157834-21-4)
- 3-Fluoro-5-(trifluoromethyl)benzeneboronic Acid (CAS 159020-59-4)
- 4-Fluoro-2-(trifluoromethyl)phenylboronic Acid (CAS 182344-16-7)
- 4-Fluoro-3-trifluoromethylbenzeneboronic acid, 97% (CAS 182344-23-6)
- [3-Fluoro-2-(trifluoromethyl)phenyl]boronic acid (CAS 850411-12-0)
- 2-Fluoro-4-(trifluoromethyl)phenylboronic Acid (CAS 503309-11-3)
- 2-Fluoro-5-(trifluoromethyl)phenylboronic Acid (CAS 352535-96-7)
- 2-Fluoro-6-(trifluoromethyl)phenylboronic Acid (CAS 313545-34-5)
Recommended Standards
- 3-Fluoro-4-(trifluoromethyl)phenylboronic Acid (CAS 864759-68-2)
- 5-Fluoro-2-(trifluoromethyl)phenylboronic Acid (CAS 928053-97-8)
- 1,1,2-Trifluoro-2-iodoethylene 2-Iodo-1,1,2-trifluoroethene 359-37-5 iodotrifluoroethylene trifluoroiodoethylene (CAS 359-37-5)
- (±)-1,2-Dibromopropane-d6 (CAS 51209-47-3)
- 1-(3-Chloropropyl)-8-methoxy-3,6-dimethylquinolin-2(1H)-one (CAS 2113977-72-1)
- 6-Bromo-N-methylhexan-1-amine (CAS 857723-11-6)
- 3,4,5-Tribromothiophene-2-carboxamide (CAS 1708199-41-0)
- 1,5-Dimethyl-3-(trifluoromethyl)-1H-pyrazole-4-carbaldehyde (CAS 1082065-80-2)
- 2-Chloro-N-(4,5,6-trifluoro-1,3-benzothiazol-2-yl)acetamide (CAS 379255-48-8)
- 8-Chloro-2-methylquinoline-3-carboxylic acid (CAS 1089898-90-7)
- 3,5-Bis(methylsulfonyl)benzenesulfonyl chloride (CAS 849035-99-0)
- 4-Butyl-2,5-dioxoimidazolidine-4-carbaldehyde (CAS 6974-17-0)
- 7-Bromo-3,4-dihydroisoquinolin-1(2H)-one (CAS 891782-60-8)
- Tirzepatide Impurity 37 (CAS CATO-C4X-324037)
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