2-Bromo-5-fluoro-4-methoxyaniline CAS 445441-58-7
| CAS No. | 445441-58-7 |
| Molecular Formula | C7H7BrFNO |
| Molecular Weight | 220.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
2-Bromo-5-fluoro-4-methoxyaniline (CAS 445441-58-7), molecular formula C7H7BrFNO and molecular weight 220.04 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Bromo-5-fluoro-4-methoxyaniline (C7H7BrFNO) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C7H7BrFNO |
| Molecular Weight | 220.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- o-(4-Bromo-2-fluorobenzyl)hydroxylamine (CAS 1031482-24-2)
- 4-Bromo-2-fluoro-5-methoxyaniline (CAS 108310-38-9)
- 3-Bromo-5-fluoro-2-methoxyaniline (CAS 1096884-89-7)
- 1-(5-Bromo-2-fluoropyridin-3-yl)ethan-1-ol (CAS 1111637-73-0)
- 1-(2-Bromo-5-fluoropyridin-4-yl)ethan-1-ol (CAS 1114523-54-4)
- 4-Bromo-3-fluoro-2-methoxyaniline (CAS 1137869-95-4)
- 3-Bromo-5-(2-fluoroethoxy)pyridine (CAS 1241752-26-0)
- 4-Bromo-2-(2-fluoroethoxy)pyridine (CAS 1248622-95-8)
Recommended Standards
- 2-Bromo-4-fluoro-6-methoxyaniline (CAS 354574-32-6)
- 2H-Nonafluorobutane (CAS 680-17-1)
- 2-Bromo-4-fluoro-5-methoxyaniline (CAS 420786-92-1)
- 3-Bromo-5-fluoro-4-methoxyaniline (CAS 875664-44-1)
- Dihexadecyl disulfide (CAS 1561-75-7)
- 2-((Tetrahydrofuran-3-yl)methoxy)nicotinic acid (CAS 1250774-51-6)
- (R)-4,7-Difluoro-2,3-dihydro-1H-inden-1-amine (CAS 1241681-62-8)
- 4-((4-Chlorobenzyl)thio)-7,9-dimethyl-2-((4-methylbenzyl)thio)pyrido[3',2':4,5]thieno[3,2-d]pyrimidine (CAS 672950-74-2)
- 2-cyano-5-fluorobenzene-1-sulfonyl chloride (CAS 612541-15-8)
- 2-Chloro-1,3-bis(bromomethyl)benzene (CAS 25006-87-5)
- Ir(PPy)2(tmd) (CAS 1171009-96-3)
- n-Cyclooctylcyclopropanecarboxamide (CAS 549519-73-5)
- Urea sulphate (CAS 19082-42-9)
- Staphylococcus Aureus Protein A (SpA)-Derived Peptide (H-2228.0005) (CAS 144979-26-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com