5-Fluoro-4-methoxy-2-nitroaniline CAS 446-20-8
| CAS No. | 446-20-8 |
| Molecular Formula | C7H7FN2O3 |
| Molecular Weight | 186.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C7H7FN2O3, 5-Fluoro-4-methoxy-2-nitroaniline contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 186.14 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
5-Fluoro-4-methoxy-2-nitroaniline (CAS 446-20-8), molecular formula C7H7FN2O3 and molecular weight 186.14 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Fluoro-4-methoxy-2-nitroaniline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H7FN2O3 |
| Molecular Weight | 186.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluoro Standards
- 4-Fluoro-2-methoxy-5-nitroaniline (CAS 1075705-01-9)
- 3-Fluoro-5-hydroxy-4-methoxybenzoic Acid (CAS 1195945-01-7)
- 4-Fluoro-5-methoxy-2-nitroaniline (CAS 125163-12-4)
- methyl 5-fluoro-2,3-dihydroxy-benzoate (CAS 1258002-30-0)
- 2-Fluoro-3-hydroxy-4-methoxybenzoic acid (CAS 1260784-66-4)
- 5-Fluoro-2-methoxy-4-nitroaniline (CAS 1435806-78-2)
- 2-Fluoro-4-methoxy-5-nitroaniline (CAS 1569986-91-9)
- 5-fluoro-3-methoxy-2-nitroaniline (CAS 1628643-07-1)
Recommended Standards
- 5-Fluoro-4-hydroxy-2-methoxybenzoic acid (CAS 208516-93-2)
- 5-Hydroxy-2-nitrobenzoic acid-d3 (CAS 2098655-73-1)
- 5-Fluoro-1-propionylpyrimidine-2,4(1H,3H)-dione (CAS 56058-99-2)
- 6-(2-Fluoroethoxy)pyridazine-3-carboxylic acid (CAS 2089732-11-4)
- 3-Cyclopropoxy-2-methylbenzaldehyde (CAS 1243384-99-7)
- 4-Bromo-N-(4-methoxyphenyl)benzamide (CAS 49747-35-5)
- 3-(2-Chlorophenyl)-6-(2,4-difluorophenoxy)-1H-pyrazolo[3,4-b]pyrazine (CAS 864301-19-9)
- 2-(Cyclopropylmethoxy)-5-fluoropyridine-4-boronic acid (CAS 2096334-21-1)
- methyl 1-ethylazetidine-2-carboxylate (CAS 54773-04-5)
- 8-chloro-1-oxaspiro[4.5]dec-6-ene (CAS 1824241-77-1)
- 13249-60-0 2-Bromo-1-octene 3761AD C8H15Br (CAS 13249-60-0)
- N-(tetrahydro-2H-thiopyran-4-yl)thiazol-2-amine (CAS 1479303-43-9)
- 3,4-Dibromo-1-(pyridin-3-ylmethyl)-1H-pyrrol-2(5H)-one (CAS 1706441-56-6)
- Myristoyl Pentapeptide -4 acetate (CAS 959610-30-1(free base))
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