alpha-(Trifluoromethyl)-4-methylbenzyl Alcohol CAS 446-65-1
| CAS No. | 446-65-1 |
| Molecular Formula | C9H9F3O |
| Molecular Weight | 190.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), alpha-(Trifluoromethyl)-4-methylbenzyl Alcohol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
alpha-(Trifluoromethyl)-4-methylbenzyl Alcohol (CAS 446-65-1) is a high-purity analytical reference standard with the molecular formula C9H9F3O and a molecular weight of 190.16 g/mol.
The molecular framework of alpha-(Trifluoromethyl)-4-methylbenzyl Alcohol (C9H9F3O) is characterized by a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C9H9F3O |
| Molecular Weight | 190.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related alpha Standards
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- 1220017-07-1 N-Benzyl-N-(4-piperidinylmethyl)-1-ethanaminedihydrochloride (CAS 1220017-07-1)
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