4-[(4-Methylbenzyl)(methylsulfonyl)amino]benzoic acid CAS 446259-00-3
| CAS No. | 446259-00-3 |
| Molecular Formula | C16H17NO4S |
| Molecular Weight | 319.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, 4-[(4-Methylbenzyl)(methylsulfonyl)amino]benzoic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 319.38 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
4-[(4-Methylbenzyl)(methylsulfonyl)amino]benzoic acid (CAS 446259-00-3), molecular formula C16H17NO4S and molecular weight 319.38 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H17NO4S |
| Molecular Weight | 319.38 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Methylbenzyl Standards
- 4-[(2-Methylbenzyl)(methylsulfonyl)amino]benzoic acid (CAS 693820-63-2)
- N-(4-methylbenzyl)-1',4'-dihydro-3'H-spiro[cyclohexane-1,2'-quinoxalin]-3'-imine (CAS 1170568-72-5)
- 3-((2-Methylbenzyl)thio)-4H-benzo[e][1,2,4]thiadiazine 1,1-dioxide (CAS 896686-38-7)
- 3-((4-Methylbenzyl)thio)-4H-benzo[e][1,2,4]thiadiazine 1,1-dioxide (CAS 896686-10-5)
- 3-(1-(4-Methylbenzyl)-3-phenyl-1h-pyrazol-4-yl)acrylic acid (CAS 1006494-72-9)
- N-(3-methylbenzyl)-1',4'-dihydro-3'H-spiro[piperidine-4,2'-quinoxalin]-3'-imine (CAS 1170107-93-3)
- N-(4-Methylbenzyl)-1H-spiro[piperidine-4,2-quinoxalin]-3-amine (CAS 1172949-94-8)
- 950455-12-6 N-(2-Methylbenzyl)-1'H-spiro[piperidine-4,2'-quinoxalin]-3'-amine MFCD14281799 (CAS 950455-12-6)
Recommended Standards
- 4-{[(3-Methylphenyl)(methylsulfonyl)amino]methyl}benzoic acid (CAS 353502-15-5)
- 4-(Methylthio)-6-oxo-1,2-diphenyl-1,6-dihydropyrimidine-5-carbonitrile (CAS 97242-69-8)
- 4-Methylbenzenesulfonic acid 2-(methylamino)-2-oxo-1(S)-phenylethyl ester (CAS 871224-68-9)
- 4-(4-Fluorophenyl)-5-((pyrimidin-2-ylthio)methyl)-4h-1,2,4-triazole-3-thiol (CAS 887205-28-9)
- 2-Chloro-5,6-dimethylpyridin-3-amine (CAS 150127-27-8)
- Ethyl 5-Hydroxy-1-methylpyrazole-3-carboxylate (CAS 51986-17-5)
- 2-Oxopropyl 2-bromobenzoate (CAS 1187828-95-0)
- 1-Isopropyl-7-methyl-1H-pyrido[2,3-d][1,3]oxazine-2,4-dione (CAS 1253791-90-0)
- Pemafibrate Impurity 39 (CAS CATO-C4X-290339)
- Pazopanib Impurity 40 (CAS CATO-C4X-172540)
- 3-(2-(2-Aminoethoxy)ethyl)oxazolidine-2,4-dione hydrochloride (CAS 1820707-14-9)
- 6-Fluoro-2-methylquinoxaline (CAS 96600-56-5)
- 3-Hydroxy-1H-pyrazolo[4,3-c]quinoline-6-carboxylic acid (CAS 1235659-45-6)
- D-Val23-Tirzepatide (CAS CATO-CPTD788911)
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