Pazopanib Impurity 40 CAS CATO-C4X-172540
| CAS No. | CATO-C4X-172540 |
| Molecular Formula | C22H25N7O2S |
| Molecular Weight | 451.54 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Pazopanib Impurity 40 (CAS CATO-C4X-172540) is a certified pharmaceutical impurity reference standard with the molecular formula C22H25N7O2S and a molecular weight of 451.54 g/mol.
Pazopanib Impurity 40 (C22H25N7O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H25N7O2S |
| Molecular Weight | 451.54 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 7 |
| Sulfur Atoms | 1 |
Related Pazopanib Standards
- Pazopanib Impurity 46(Mixture of Isomers) (CAS CATO-C4X-172546)
- Pazopanib Impurity 54 (CAS CATO-C4X-172554)
- Pazopanib Impurity N7 (CAS 1414375-50-0)
- Pazopanib Impurity 2 (CAS 1821666-73-2)
- Pazopanib Impurity 16 (CAS CATO-C4X-172516)
- Pazopanib-d6 (CAS 1219592-01-4)
- Pazopanib-d3 Hydrochloride (CAS CATO-CCAD304303)
- Pazopanib Impurity 43 (CAS CATO-C4X-172543)
Recommended Standards
- Dasatinib Impurity 35 (CAS CATO-C4X-160735)
- 2-((6-(Adamantan-1-yl)-3-cyano-4-(trifluoromethyl)pyridin-2-yl)thio)-N,N-diethylacetamide (CAS 488733-83-1)
- Dasatinib Impurity 34 (CAS CATO-C4X-160734)
- 6-(Adamantan-1-yl)-3-amino-N,N-diethyl-4-(trifluoromethyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 489405-41-6)
- Phenoxymethylpenicillin EP Impurity B (CAS 122-59-8)
- Aprepitant Impurity 26 (CAS CATO-C4X-114126)
- Lamotrigine Impurity 22 (CAS CATO-C4X-167222)
- 6-Chloro-4-hydroxy-N-(4-methylthiazol-2-yl)quinoline-3-carboxamide (CAS 955314-73-5)
- 2,6-Dichloro-n-(1-cyanocyclopentyl)benzamide (CAS 912763-66-7)
- (S,E)-N-(3-Bromo-5-fluorobenzylidene)-2-methylpropane-2-sulfinamide (CAS 1715032-45-3)
- Oxytocin Open Ring Impurity (CAS 17912-60-6(free base))
- N,N-dimethyl-2-(5-nitro-2H-indazol-2-yl)ethan-1-amine (CAS 860649-95-2)
- 2-Chloro-3,6-dimethylquinoline (CAS 132118-28-6)
- Semaglutide impurity 202 (CAS CATO-C4X-2226202)
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