3-Methyl-4-(3-(trifluoromethyl)phenyl)isoxazol-5-amine CAS 446276-00-2
| CAS No. | 446276-00-2 |
| Molecular Formula | C11H9F3N2O |
| Molecular Weight | 242.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
3-Methyl-4-(3-(trifluoromethyl)phenyl)isoxazol-5-amine (CAS 446276-00-2), molecular formula C11H9F3N2O and molecular weight 242.20 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 3-Methyl-4-(3-(trifluoromethyl)phenyl)isoxazol-5-amine is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 242.20 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H9F3N2O |
| Molecular Weight | 242.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Methyl Standards
- 5-Methyl-1-(5-(trifluoromethyl)pyridin-2-yl)-1,2-dihydro-3h-pyrazol-3-imine (CAS 1171925-31-7)
- 3a-(Trifluoromethyl)-2,3,3a,4-tetrahydro-1H-benzo[d]pyrrolo[1,2-a]imidazol-1-one (CAS 1191278-87-1)
- alpha-(Trifluoromethyl)-1-phenyl-1H-pyrazole-4-methanol (CAS 1275913-48-8)
- 1-(4-(Trifluoromethyl)benzyl)-1H-1,2,4-triazol-3-amine (CAS 1291723-68-6)
- 1-[1-methyl-5-(trifluoromethyl)-1h-1,3-benzodiazol-2-yl]ethan-1-one (CAS 1312139-07-3)
- 3-Oxo-1-(trifluoromethyl)-2,3,5,6,7,8-hexahydroisoquinoline-4-carbonitrile (CAS 1334490-86-6)
- 2-Benzyl-5-(trifluoromethyl)-1,2-dihydro-3H-pyrazol-3-one (CAS 143706-79-0)
- 1-(4-(Trifluoromethyl)benzyl)-1H-1,2,3-triazol-4-amine (CAS 1510209-73-0)
Recommended Standards
- 3-methyl-1-[5-(trifluoromethyl)pyridin-2-yl]-1H-pyrazol-5-amine (CAS 926234-78-8)
- 4-(1-Methylhydrazinyl)-2-(trifluoromethyl)quinazoline (CAS 303148-88-1)
- 3-Methyl-1-[3-(trifluoromethyl)phenyl]-4,5-dihydro-1H-pyrazol-5-one (CAS 321-05-1)
- 4-Cyclopropyl-6-(trifluoromethyl)-1h-pyrazolo[3,4-b]pyridin-3-amine (CAS 832739-88-5)
- (4-Ethynyl-3-fluorophenyl)methanol (CAS 1678527-77-9)
- (2,6-Naphthalenedimethylene)bis(triphenylphosphonium bromide) hydrate (CAS 25075-81-4)
- N1-Acetyl Triethylenetetramine (CAS 141998-21-2)
- 2-(4-Aminophenyl)-1,2-dihydro-7-[(1-oxido-2-pyridinyl)methoxy]-1-oxo-4-(3,4,5-trimethoxyphenyl)-3-isoquinolinecarboxylic Acid methyl Ester MonoHCl (CAS 260414-73-1)
- 9-Chloro-3-methyl-5-nitroacridine (CAS 255713-06-5)
- Ethyl 5-amino-1-(3,4-dimethylphenyl)-1H-pyrazole-3-carboxylate (CAS 866838-06-4)
- 2-Bromo-3-iodobenzaldehyde (CAS 1261850-39-8)
- Vonoprazan Impurity 256 (CAS CATO-C4X-1020256)
- 2-Chloro-5-ethoxybenzo[d]thiazole (CAS 855275-58-0)
- Tripeptide-10 citrulline (CAS 960531-53-7)
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