Ethyl 2-(2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)hydrazinyl)-2-oxoacetate CAS 446276-05-7
| CAS No. | 446276-05-7 |
| Molecular Formula | C10H9ClF3N3O3 |
| Molecular Weight | 311.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Ethyl 2-(2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)hydrazinyl)-2-oxoacetate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Ethyl 2-(2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)hydrazinyl)-2-oxoacetate (CAS 446276-05-7) is a high-purity analytical reference standard with the molecular formula C10H9ClF3N3O3 and a molecular weight of 311.64 g/mol.
The molecular framework of Ethyl 2-(2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)hydrazinyl)-2-oxoacetate (C10H9ClF3N3O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H9ClF3N3O3 |
| Molecular Weight | 311.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Ethyl Standards
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- 447438-06-4 5-Chloro-2-methoxy-4-[(trifluoroacetyl)amino]benzoic Acid Methyl Ester Methyl 5-Chloro-2-methoxy-4-trifluoroacetamidobenzoate (CAS 447438-06-4)
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Recommended Standards
- Dimethyl 2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)malonate (CAS 477859-76-0)
- 1-bromo-8-chloro-3-(methoxymethoxy)naphthalene (CAS 2454490-96-9)
- Lodoxamide (CAS 53882-12-5)
- 3-[4-(trifluoromethyl)phenyl]-1,2-oxazole-5-sulfonyl chloride (CAS 2044871-72-7)
- 2-(hexadecyloxy)-1,3-Propanediol (CAS 1931-78-8)
- 2-Iodo-1-(oxan-2-yl)-1h-imidazole (CAS 1047626-77-6)
- 2-Ethyl-4-propoxyquinazoline (CAS 815590-76-2)
- Ethyl (2-oxopent-4-en-1-yl)carbamate (CAS 1823371-59-0)
- O6-(2-Hydroxyethyl)-2'-deoxyguanosine (CAS 111447-35-9)
- 3-(((((9H-fluoren-9-yl)methoxy)carbonyl)amino)methyl)bicyclo[1.1.1]Pentane-1-carboxylic acid (CAS 2137734-35-9)
- 2-(Chloromethyl)-6,7-dihydro-1H-[1,4]dioxino[2,3-f]benzimidazole hydrochloride (CAS 1211430-27-1)
- Diisopropylamino Borane (CAS 22092-92-8)
- 2,6-Dimethyl-1,4-dioxane (CAS 10138-17-7)
- Tirzepatide Impurity 50 (CAS CATO-C4X-324050)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com