1-Methoxy-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile CAS 446276-10-4
| CAS No. | 446276-10-4 |
| Molecular Formula | C6H5N3O3 |
| Molecular Weight | 167.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 1-Methoxy-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
1-Methoxy-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile (CAS 446276-10-4), molecular formula C6H5N3O3 and molecular weight 167.12 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-Methoxy-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile (C6H5N3O3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H5N3O3 |
| Molecular Weight | 167.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
Related Methoxy Standards
- 6-Methoxy-[1,2,5]oxadiazolo[3,4-b]pyrazin-5-amine (CAS 339338-74-8)
- 5-Methoxy-6-methylpicolinic acid (CAS 100960-94-9)
- 2-Methoxy-4-methylnicotinic acid (CAS 1211516-03-8)
- 4-Methoxy-6-methylnicotinic acid (CAS 1211530-77-6)
- 6-Methoxy-5-methylnicotinic acid (CAS 1211531-94-0)
- 5-Methoxy-4-methylnicotinic acid (CAS 1211535-00-0)
- 5-Methoxy-2-methylisonicotinic acid (CAS 1211578-07-2)
- 2-Methoxy-5-methylisonicotinic acid (CAS 1211581-36-0)
Recommended Standards
- 1H-Pyrrolo[3,2-d]pyrimidine-2,4,6(3H,5H,7H)-trione (CAS 467421-29-0)
- 2,4-Pyridinedicarboxylic Acid (CAS 499-80-9)
- [1,3]Dioxolo[4,5-b]pyridine-7-carboxylic acid (CAS 692059-95-3)
- 2h-[1,3]dioxolo[4,5-c]pyridine-6-carboxylic acid (CAS 521278-13-7)
- 4-Cyclohexylsulfonylbutanoic acid (CAS 922190-00-9)
- 1-(2-Chloropyridin-3-yl)-3-(methyl(oxo)(phenyl)-lambda6-sulfanylidene)urea (CAS 650615-80-8)
- Cucurbitadienol (CAS 35012-08-9)
- (4-Aminophenyl)(4-(dimethylamino)piperidin-1-yl)methanone (CAS 50534-08-2)
- N-((1H-indol-4-yl)methyl)-2-phenylethan-1-amine (CAS 944897-34-1)
- 2-Amino-5-(Pentafluorothio)benzonitrile (CAS 159727-27-2)
- Methyl 2-ethynylnicotinate (CAS 379670-43-6)
- Apalutamide Impurity 98 (CAS CATO-C4X-274998)
- lithium(1+) ion 2-{2-[(oxolan-2-ylmethyl)amino]-1,3-thiazol-4-yl}acetate (CAS 2044713-86-0)
- D-[Asp]9-Semaglutide (CAS CATO-CPTD788631)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com