1H-Pyrrolo[3,2-d]pyrimidine-2,4,6(3H,5H,7H)-trione CAS 467421-29-0
| CAS No. | 467421-29-0 |
| Molecular Formula | C6H5N3O3 |
| Molecular Weight | 167.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1H-Pyrrolo[3,2-d]pyrimidine-2,4,6(3H,5H,7H)-trione (CAS 467421-29-0), molecular formula C6H5N3O3 and molecular weight 167.12 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1H-Pyrrolo[3,2-d]pyrimidine-2,4,6(3H,5H,7H)-trione (C6H5N3O3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1H-Pyrrolo[3,2-d]pyrimidine-2,4,6(3H,5H,7H)-trione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H5N3O3 |
| Molecular Weight | 167.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
Related H Standards
- 4H-Pyrrolo[2,3-d]thiazole-5-carboxamide (CAS 1934648-57-3)
- Pyrrolo[2,1-b]thiazole-6-carboxylic acid (CAS 956293-18-8)
- 1H-Pyrrolo[2,3-b]pyridin-5-amine, 4-chloro- (CAS 930293-37-1)
- 2-{pyrrolo[2,1-f][1,2,4]triazin-5-yl}acetonitrile (CAS 1935504-47-4)
- 1-(4H-Pyrrolo[2,3-d]thiazol-5-yl)ethanone (CAS 141764-97-8)
- 4H-Pyrrolo[3,2-d]thiazole-5-carboxylic acid (CAS 1007386-66-4)
- 1H-Pyrrolo[2,3-f]quinoline (CAS 233-36-3)
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Recommended Standards
- [1,3]Dioxolo[4,5-b]pyridine-7-carboxylic acid (CAS 692059-95-3)
- 1-Methoxy-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile (CAS 446276-10-4)
- [1,3]Dioxolo[4,5-b]pyridine-6-carboxylic acid (CAS 76470-41-2)
- 2,4-Pyridinedicarboxylic Acid (CAS 499-80-9)
- 2-(2-Iodo-7-methoxyquinolin-3-yl)-5,7-dimethyl-1,3-diazaadamantan-6-one (CAS 1442533-41-6)
- Butyl(3-phenylbutyl)amine hydrochloride (CAS 1240581-91-2)
- (2-(Isopentyloxy)-5-methylphenyl)methanol (CAS 1343795-39-0)
- 5-Chloro-2-nitrobenzenethiol (CAS 14371-79-0)
- 2-Methyl-2-(pyrrolidin-1-yl)propan-1-amine (CAS 887405-25-6)
- 3-Amino-N-(3,4-difluorophenyl)-6-ethyl-4-(trifluoromethyl)-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide (CAS 939888-79-6)
- (R)-N-Boc-4-(iodomethyl)-2,2-dimethyloxazolidine (CAS 1231672-20-0)
- 53169-24-7 Cerium zirconium oxide (CeZrO4) Cerium zirconium tetraoxide Cerium zirconate EINECS 258-407-6 (CAS 53169-24-7)
- Salbutamol EP Impurity H(HCl) (CAS 2252153-95-8)
- Peptide Impurity 11 X TFA Salt (CAS CATO-CPTD788811)
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