3-(Cyclohexyl(methyl)amino)-1,1,1-trifluoropropan-2-ol CAS 446276-15-9

Purity 97%+In StockPharmaceutical Standards
CAS No.446276-15-9
Molecular FormulaC10H18F3NO
Molecular Weight225.25 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-(Cyclohexyl(methyl)amino)-1,1,1-trifluoropropan-2-ol CAS 446276-15-9 chemical structure

Description

The occurrence of 3-(Cyclohexyl(methyl)amino)-1,1,1-trifluoropropan-2-ol is closely related to an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

3-(Cyclohexyl(methyl)amino)-1,1,1-trifluoropropan-2-ol (CAS 446276-15-9), molecular formula C10H18F3NO and molecular weight 225.25 g/mol, is a CATO reference standard with documented purity and traceability.

3-(Cyclohexyl(methyl)amino)-1,1,1-trifluoropropan-2-ol (C10H18F3NO) contains an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H18F3NO
Molecular Weight225.25 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)1.0
CAS Registry Year (est.)2025
Halogen ContentF-containing
Nitrogen Atoms1

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