3-(3-Fluorophenoxy)aniline CAS 446884-28-2
| CAS No. | 446884-28-2 |
| Molecular Formula | C12H10FNO |
| Molecular Weight | 203.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-(3-Fluorophenoxy)aniline (CAS 446884-28-2) is a high-purity analytical reference standard with the molecular formula C12H10FNO and a molecular weight of 203.21 g/mol.
The molecular framework of 3-(3-Fluorophenoxy)aniline (C12H10FNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-(3-Fluorophenoxy)aniline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H10FNO |
| Molecular Weight | 203.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluorophenoxy Standards
- 2-(2-Fluorophenoxy)aniline (CAS 391906-76-6)
- 2-(3-Fluorophenoxy)aniline (CAS 640766-67-2)
- 2-(4-Fluorophenoxy)aniline (CAS 3169-71-9)
- 3-(2-Fluorophenoxy)aniline (CAS 850621-04-4)
- 3-(4-Fluorophenoxy)aniline (CAS 203302-94-7)
- 4-(2-Fluorophenoxy)aniline (CAS 305801-12-1)
- 4-(3-Fluorophenoxy)aniline (CAS 307308-62-9)
- 4-(4-Fluorophenoxy)aniline (CAS 36160-82-4)
Recommended Standards
- 2-fluoro-7-isocyanato-tricyclo[6.3.0.0³⁶]undeca-1(8),2,6-triene (CAS 2676867-26-6)
- 3-(Difluoromethylthio)benzamide (CAS 261944-10-9)
- 2-Fluoro-6-(4-methoxyphenyl)pyridine (CAS 847226-09-9)
- 3-Fluoro-4-phenoxyaniline (CAS 39177-22-5)
- Leuprolide(5-9)TFA salt (CAS 129244-90-2(Free Base))
- 2-(2-Chloro-3-cyano-5-(difluoromethyl)pyridin-4-yl)acetic acid (CAS 1804668-59-4)
- (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(1-(tert-butoxycarbonyl)-1H-indol-3-yl)-2-methylpropanoic acid (CAS 1315449-98-9)
- Beclomethasone dipropionate Impurity 30 (CAS 2758770-17-9)
- Ethyl 3-(N-(3-fluorophenyl)sulfamoyl)benzo[b]thiophene-2-carboxylate (CAS 932354-17-1)
- 3-Ethoxy-2-(methylsulfonyl)acrylonitrile (CAS 104007-26-3)
- H-Phe(4-Br)-Ome.HCl (CAS 99359-32-7)
- 2,3,6-Trifluoro-4-(trifluoromethyl)aniline (CAS 1357626-57-3)
- 3-(5-Amino-2-methoxyphenyl)-1,3-oxazolidin-2-one (CAS 1042623-24-4)
- Acetyl-(Leu28·31)-Neuropeptide Y (24-36) (CAS 155709-24-3)
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