Beclomethasone dipropionate Impurity 30 CAS 2758770-17-9
| CAS No. | 2758770-17-9 |
| Molecular Formula | C24H29BrO6 |
| Molecular Weight | 493.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C24H29BrO6, Beclomethasone dipropionate Impurity 30 contains a flavonoid core, a hydroxyl group, an ether linkage, bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 493.39 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Beclomethasone dipropionate Impurity 30 (CAS 2758770-17-9, C24H29BrO6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H29BrO6 |
| Molecular Weight | 493.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Halogen Content | Br-containing |
Related Beclomethasone Standards
- Beclomethasone Hemisuccinate (CAS 75899-57-9)
- Beclomethasone 17-Propionate-d5 (CAS CATO-C4X-147425)
- Beclomethasone dipropionate EP Impurity H-D5 (CAS 5534-18-9 (Non-Labelled))
- Beclomethasone-17-Monopropionate-d3 (CAS CATO-C4X-147426)
- Beclomethasone Dipropionate-d6 (CAS CATO-C4X-147424)
- Beclomethasone Dipropionate-d10 (CAS CATO-CCAD301383)
- Beclomethasone dipropionate Impurity 23 (CAS CATO-C4X-147423)
- Beclomethasone dipropionate Impurity 41 (CAS CATO-C4X-147441)
Recommended Standards
- 4-[(2E)-3-(5-Bromo-2-methoxyphenyl)prop-2-enoyl]phenyl 4-tert-butylbenzoate (CAS 306730-17-6)
- Tolvaptan Impurity 25 (CAS 2921676-63-1)
- (4-((S)-N-((S)-1-Amino-1-oxo-3-phenylpropan-2-yl)pyrrolidine-2-carboxamido)-1-hydroxybutane-1,1-diyl)diphosphonic acid (CAS 192656-82-9)
- Indoxacarb Impurity 5 (CAS CATO-C4X-24845)
- Leuprorelin Impurity 53 (CAS CATO-C4X-182253)
- (See C4X-125491)Tirofiban Impurity 52 (CAS CATO-C4X-125452)
- Empagliflozin Impurity 79 (CAS 2452301-24-3)
- Methyl (2-hydroxypropyl)carbamate (CAS 92633-41-5)
- rac 4-Nitro Deprenyl HCl (CAS 13571-00-1)
- 1-tert-Butyl 2-ethyl 4-bromo-1H-pyrrole-1,2-dicarboxylate, 97% (CAS 516465-80-8)
- 2-Propenoic acid, 2-methyl-, methyl ester, polymer with 1,3-butadiene, ethenylbenzene, 2-ethylhexyl 2-propenoate and 2-propenenitrile (CAS 41585-11-9)
- Sodium 3-carboxy-2,3-dimercaptopropanoate (CAS 71799-86-5)
- PDD 00017273 (CAS 1945950-21-9)
- Neuropeptide Y (3-36) (human, rat) trifluoroacetate salt (CAS 150138-78-6)
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