2-(Trifluoromethyl)benzonitrile CAS 447-60-9
| CAS No. | 447-60-9 |
| Molecular Formula | C8H4F3N |
| Molecular Weight | 171.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(Trifluoromethyl)benzonitrile (CAS 447-60-9) is a high-purity analytical reference standard with the molecular formula C8H4F3N and a molecular weight of 171.12 g/mol.
2-(Trifluoromethyl)benzonitrile (C8H4F3N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(Trifluoromethyl)benzonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H4F3N |
| Molecular Weight | 171.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethyl Standards
- 4-methyl-2-(trifluoromethyl)-1,3-dioxolan-2-amine (CAS 1955518-08-7)
- 3-(Trifluoromethyl)benzonitrile (CAS 368-77-4)
- 2-(trifluoromethyl)thiomorpholine (CAS 1446485-41-1)
- 2-ethyl-2-(trifluoromethyl)butan-1-ol (CAS 1955553-46-4)
- 1-(Trifluoromethyl)-3-fluorobenzene 1-Fluoro-3-(trifluoromethyl)benzene 401-80-9 Benzene, 1-fluoro-3-(trifluoromethyl)- NSC-10315 NSC10315 Toluene,.alpha.,.alpha.,.alpha.-tetrafluoro- Toluene,.alpha.,.alpha.-m-tetrafluoro- Trifluoromethyl-3-fluorobenzene m,.alpha.,.alpha.-Tetrafluorotoluene m-Fluorobenzotrifluoride (CAS 401-80-9)
- [3-(trifluoromethyl)-1H-pyrazol-5-yl]hydrazine (CAS 2566599-97-9)
- 5-(trifluoromethyl)-1,2,4-triazin-3-amine (CAS 425378-65-0)
- 2-(trifluoromethyl)pyrimidin-5-ol (CAS 100991-09-1)
Recommended Standards
- 2-(2,3,4-Trifluorophenyl)acetonitrile (CAS 243666-13-9)
- 2,2,2-Trifluoroethyl n,n-dimethylcarbamate (CAS 407-43-2)
- (2S,3R)-2-Amino-4,4,4-trifluoro-3-methylbutanoic acid (CAS 409333-57-9)
- 2,2,2-Trifluoroethyl n-ethylcarbamate (CAS 854889-47-7)
- 2-Amino-7-(chloromethyl)pteridin-4(1H)-one HCl (CAS 1391054-83-3)
- (3-Iodopropyl)cyclopentane (CAS 106211-63-6)
- N'-(2-(2,4-dichlorophenoxy)acetyl)methanesulfonohydrazide (CAS 1024406-71-0)
- 6-(Trifluoromethyl)-1,2,3,4-tetrahydroquinoline-3-carboxylic acid (CAS 1706452-49-4)
- 2-(5-Methylfuran-2-yl)-2-morpholinoethan-1-amine (CAS 875160-04-6)
- (3,4-Dihydro-2H-benzo-[b][1,4]oxazin-7-yl)boronic acid (CAS 1253911-87-3)
- (6-(Piperidin-1-yl)pyridin-2-yl)boronic acid (CAS 1315351-02-0)
- N-Propylbenzene (CAS 103-65-1)
- N-(6-Chloropyridazin-3-yl)pivalamide (CAS 147362-88-7)
- Peptide Impurity 70 TFA Salt (CAS CATO-CPTD788570)
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