1-(3-Chlorophenyl)-3-(1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl)urea CAS 448189-13-7
| CAS No. | 448189-13-7 |
| Molecular Formula | C11H15ClN2O4 |
| Molecular Weight | 274.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 274.70 g/mol gives 1-(3-Chlorophenyl)-3-(1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl)urea distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-(3-Chlorophenyl)-3-(1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl)urea (CAS 448189-13-7), molecular formula C11H15ClN2O4 and molecular weight 274.70 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(3-Chlorophenyl)-3-(1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl)urea (C11H15ClN2O4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-(3-Chlorophenyl)-3-(1,3-dihydroxy-2-(hydroxymethyl)propan-2-yl)urea under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H15ClN2O4 |
| Molecular Weight | 274.70 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorophenyl Standards
- 2-(2-Chlorophenyl)-4-cyclopropylpyrimidine-5-carboxylic acid (CAS 1283933-33-4)
- 2-(4-Chlorophenyl)-4-cyclopropylpyrimidine-5-carboxylic acid (CAS 1284418-58-1)
- (3-Chlorophenyl)(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methanone (CAS 727994-89-0)
- 1-(2-Chlorophenyl)-3,4-dimethylpyrano[2,3-c]pyrazol-6(1H)-one (CAS 85094-16-2)
- 1-(3-Chlorophenyl)-3,4-dimethylpyrano[2,3-c]pyrazol-6(1H)-one (CAS 96138-46-4)
- 1-(4-Chlorophenyl)-3-(2-hydroxyphenyl)propane-1,3-dione (CAS 65599-34-0)
- 1-(4-Chlorophenyl)-3,4-dimethylpyrano[2,3-c]pyrazol-6(1H)-one (CAS 74169-54-3)
- 2-Acetyl-4-chlorophenyl benzoate (CAS 4010-29-1)
Recommended Standards
- (E)-3-(2-(3-chlorophenoxy)phenyl)acrylic acid (CAS 338393-65-0)
- 4-(2-Chlorobenzoyl)phenyl acetate (CAS 185606-03-5)
- 1-(5-Chloro-2-hydroxyphenyl)-3-phenylpropane-1,3-dione (CAS 5067-25-4)
- 4-(3-Chlorobenzoyl)phenyl acetate (CAS 185606-02-4)
- 2-((2-Fluorobenzyl)thio)-3-isobutylthieno[3,2-d]pyrimidin-4(3H)-one (CAS 1788532-80-8)
- (R)-2,2,2-Trifluoro-1-(3-(trifluoromethyl)phenyl)ethan-1-ol (CAS 80446-61-3)
- 2-(((9H-fluoren-9-yl)methoxy)carbonylamino)acrylic acid (CAS 261522-33-2)
- 3-ISoxazol-5-ylpiperidine hydrochloride (CAS 1367953-16-9)
- 2-(2-Iodo-6-methoxyquinolin-3-yl)-5,7-dimethyl-1,3-diazaadamantan-6-ol (CAS 1442541-63-0)
- 4-(1h-1,2,4-Triazol-1-yl)butan-1-ol (CAS 1153126-19-2)
- Vericiguat Impurity 12 (CAS CATO-C4X-289612)
- 1-(4-Bromophenyl)-1H-indazole (CAS 838820-83-0)
- Tinidazole impurity 28 (CAS CATO-C4X-193028)
- [2-31]-Semaglutide C (x TFA Salt) (CAS CATO-C4X-2226118)
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