2-(1-Hydroxy-2-methylpropan-2-yl)-2,3-dihydro-1h-isoindole-1,3-dione CAS 4490-74-8
| CAS No. | 4490-74-8 |
| Molecular Formula | C12H13NO3 |
| Molecular Weight | 219.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-(1-Hydroxy-2-methylpropan-2-yl)-2,3-dihydro-1h-isoindole-1,3-dione (CAS 4490-74-8), a certified reference material (molecular formula C12H13NO3, MW 219.24 g/mol) for analytical method development and quality control.
2-(1-Hydroxy-2-methylpropan-2-yl)-2,3-dihydro-1h-isoindole-1,3-dione (C12H13NO3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(1-Hydroxy-2-methylpropan-2-yl)-2,3-dihydro-1h-isoindole-1,3-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H13NO3 |
| Molecular Weight | 219.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 1 |
Related Hydroxy Standards
- Ethyl 3-hydroxy-5-methyl-1H-indole-2-carboxylate (CAS 1060803-17-9)
- 3-Hydroxy-1-isobutylpyrido[2,3-b]pyrazin-2(1H)-one (CAS 1443285-87-7)
- Ethyl 3-hydroxy-4-methyl-1H-indole-2-carboxylate (CAS 153501-38-3)
- 7-Hydroxy-3-methyl-1H,3H,3aH,4H,5H-[1,3]oxazolo[3,4-a]quinolin-1-one (CAS 1824633-17-1)
- (R)-2-(4-Hydroxy-2-butyl)isoindoline-1,3-dione (CAS 245728-73-8)
- (S)-2-(4-Hydroxy-2-butyl)isoindoline-1,3-dione (CAS 545376-10-1)
- 1-Ethyl-5-hydroxy-2-methyl-1h-indole-3-carboxylic acid (CAS 38189-61-6)
- 2-Ethyl-6-hydroxy-N-methylbenzofuran-3-carboxamide (CAS 638217-12-6)
Recommended Standards
- 2-(1H-Indol-3-yl)-nicotinonitrile (CAS 3191-30-8)
- 2-(1-Oxoisoindolin-2-yl)butanoic acid (CAS 950252-65-0)
- 2-(1H-benzo[d]imidazol-2-yl)benzonitrile (CAS 76889-76-4)
- 2-(2-(Allyloxy)benzylidene)hydrazinecarboxamide (CAS 3256-41-5)
- 2-Amino-1-cyclobutylethan-1-one (CAS 1511620-22-6)
- 1,4-dichloro-4-methylpentane (CAS 54305-91-8)
- Pentyl 2-(3-oxopiperazin-2-yl)acetate (CAS 1025736-40-6)
- Thioctic acid Impurity 33 (CAS 50628-92-7)
- Perampanel Impurity 26 (CAS CATO-C4X-243026)
- 6-METHYL-3-(PIPERIDIN-4-YL)BENZO[D] OXAZOL-2(3H)-ONE HCL (CAS 173843-58-8)
- Budesonide Impurity 14 (CAS 5541-37-7)
- 7-Bromo-6-fluorobenzo[d]oxazole (CAS 1445995-78-7)
- 2-(Chloromethyl)acrylamide (CAS 61152-88-3)
- 141801-03-8 IL-1 Receptor Peptide (human) (CAS 141801-03-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com