N-(4-Chloro-2-methoxy-5-methylphenyl)-2,3-dihydrobenzo[b][1,4]dioxine-2-carboxamide CAS 449170-44-9
| CAS No. | 449170-44-9 |
| Molecular Formula | C17H16ClNO4 |
| Molecular Weight | 333.77 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 333.77 g/mol gives N-(4-Chloro-2-methoxy-5-methylphenyl)-2,3-dihydrobenzo[b][1,4]dioxine-2-carboxamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
N-(4-Chloro-2-methoxy-5-methylphenyl)-2,3-dihydrobenzo[b][1,4]dioxine-2-carboxamide (CAS 449170-44-9) is a high-purity analytical reference standard with the molecular formula C17H16ClNO4 and a molecular weight of 333.77 g/mol.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, N-(4-Chloro-2-methoxy-5-methylphenyl)-2,3-dihydrobenzo[b][1,4]dioxine-2-carboxamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 333.77 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures N-(4-Chloro-2-methoxy-5-methylphenyl)-2,3-dihydrobenzo[b][1,4]dioxine-2-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H16ClNO4 |
| Molecular Weight | 333.77 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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- 2-(5-Chloro-2-ethoxy-4-formylphenoxy)-N-phenylacetamide (CAS 834896-05-8)
- 2-Chloro-N-(5-(4-fluorophenyl)-1,3,4-thiadiazol-2-yl)benzamide (CAS 391226-48-5)
- 4-((2-Chloro-6-fluorobenzylidene)amino)-3-(pyridin-2-yl)-1H-1,2,4-triazole-5(4H)-thione (CAS 497823-54-8)
- 4-Chloro-2-(4-methoxyphenyl)-5-(4-oxopiperidin-1-yl)pyridazin-3(2H)-one (CAS 338413-78-8)
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Recommended Standards
- N-(3-chlorophenyl)-2-(2-ethoxy-4-formylphenoxy)acetamide (CAS 247592-72-9)
- N-(4-chlorophenyl)-2-(2-ethoxy-4-formylphenoxy)acetamide (CAS 247592-70-7)
- N-(5-(4-Chlorophenyl)-1,2,4-thiadiazol-3-yl)-2-fluorobenzamide (CAS 690645-61-5)
- n-(2-Chlorophenyl)-2-(2-ethoxy-4-formylphenoxy)acetamide (CAS 575499-01-3)
- 2-Undecanol (CAS 1653-30-1)
- 29965-34-2 Benzenesulfonic acid, 4-ethenyl-, ammonium salt (1:1), homopolymer Benzenesulfonic acid, 4-ethenyl-, ammonium salt, homopolymer p-Styrenesulfonic acid, ammonium salt, homopolymer (CAS 29965-34-2)
- Benzyl 2-isopropyl-1,3-dioxohexahydroimidazo[1,5-a]pyrazine-7(1H)-carboxylate (CAS 1353497-26-3)
- cis-tert-Butyl 3a-phenylhexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate (CAS 1251007-24-5)
- 1,5-Dibromo-3-methyl-2-nitrobenzene (CAS 76435-23-9)
- 2-Bromo-N-{4-[(4-methyl-1-piperidinyl)carbonyl]-phenyl}acetamide (CAS 1138442-63-3)
- Puerarin (CAS 3681-99-0)
- Ethyl 6-(3,4-dimethylphenyl)-6-oxohexanoate (CAS 898793-09-4)
- pent-4-yn-2-amine (CAS 58456-49-8)
- Neuropeptide VF (124-131) (human) (CAS 311309-27-0)
Why CATO?
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