4-((2-Chloro-6-fluorobenzylidene)amino)-3-(pyridin-2-yl)-1H-1,2,4-triazole-5(4H)-thione CAS 497823-54-8
| CAS No. | 497823-54-8 |
| Molecular Formula | C14H9ClFN5S |
| Molecular Weight | 333.77 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-((2-Chloro-6-fluorobenzylidene)amino)-3-(pyridin-2-yl)-1H-1,2,4-triazole-5(4H)-thione (C14H9ClFN5S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
4-((2-Chloro-6-fluorobenzylidene)amino)-3-(pyridin-2-yl)-1H-1,2,4-triazole-5(4H)-thione (CAS 497823-54-8), molecular formula C14H9ClFN5S and molecular weight 333.77 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-((2-Chloro-6-fluorobenzylidene)amino)-3-(pyridin-2-yl)-1H-1,2,4-triazole-5(4H)-thione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H9ClFN5S |
| Molecular Weight | 333.77 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 3-(4-Chlorobenzamido)-3-(4-methoxyphenyl)propanoic acid (CAS 332052-54-7)
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- 3-(((Benzyloxy)carbonyl)amino)-3-(4-chlorophenyl)propanoic acid (CAS 773867-63-3)
- 4-(3-(2-Chlorophenyl)-5-methylisoxazole-4-carbonyl)piperazine-1-carbaldehyde (CAS 866152-61-6)
- EThyl 2-bromo-2-methyl-3-oxobutanoate (CAS 32116-05-5)
- 6-Bromo-3-formylimidazo[1,2-a]pyridine-7-carboxylic acid (CAS 2044871-61-4)
- 9-(Naphthalen-1-yl)-10-(naphthalen-2-yl)anthracene (CAS 855828-36-3)
- 2-Phenoxy-2-phenylethan-1-ol (CAS 53574-80-4)
- Azaspiracid-4 (CAS 344422-49-7)
- [5-methoxy-4-(2-methylbutoxy)-2-nitrophenyl]methanol (CAS 1443982-12-4)
- 1-(3-Amino-4-methylphenyl)imidazolidin-2-one (CAS 1038247-59-4)
- (E)-3-(4-(benzyloxy)-3-ethoxyphenyl)acrylic acid (CAS 565174-23-4)
- 2-Ethyl-5-fluoro-4-methoxybenzaldehyde (CAS 1234845-81-8)
- Semaglutide Impurity 142 (CAS CATO-C4X-2226142)
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