Ethyl 5-(2-chloroacetamido)-4-cyano-3-methylthiophene-2-carboxylate CAS 449177-08-6
| CAS No. | 449177-08-6 |
| Molecular Formula | C11H11ClN2O3S |
| Molecular Weight | 286.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 5-(2-chloroacetamido)-4-cyano-3-methylthiophene-2-carboxylate.
CATO supplies Ethyl 5-(2-chloroacetamido)-4-cyano-3-methylthiophene-2-carboxylate (CAS 449177-08-6), a certified reference material (molecular formula C11H11ClN2O3S, MW 286.73 g/mol) for analytical method development and quality control.
Based on its molecular formula C11H11ClN2O3S, Ethyl 5-(2-chloroacetamido)-4-cyano-3-methylthiophene-2-carboxylate contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 286.73 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Ethyl 5-(2-chloroacetamido)-4-cyano-3-methylthiophene-2-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H11ClN2O3S |
| Molecular Weight | 286.73 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Ethyl Standards
- 2-(2-Chloroacetamido)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamide (CAS 519016-70-7)
- 2-(2-Chloroacetamido)-6-methyl-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide (CAS 436090-09-4)
- Methyl 2-(2-chloroacetamido)-4,5-dimethoxybenzoate (CAS 285138-76-3)
- 5-(2-Chloroacetamido)-4-cyano-N,N,3-trimethylthiophene-2-carboxamide (CAS 908509-58-0)
- Ethyl 2-(2-chloroacetamido)-4-cyclopropylthiophene-3-carboxylate (CAS 735319-21-8)
- Ethyl 2-(2-chloroacetamido)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate (CAS 203385-15-3)
- Methyl 2-(2-chloroacetamido)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate (CAS 300559-61-9)
- N-[3-(2-chloroacetamido)phenyl]benzamide (CAS 1233188-83-4)
Recommended Standards
- Ethyl 2-(chloromethyl)-5-methyl-4-oxo-3H,4H-thieno[2,3-d]pyrimidine-6-carboxylate (CAS 89567-06-6)
- Ethyl 6-(2-chloro-4-fluorophenyl)-6-oxohexanoate (CAS 951886-25-2)
- 8-(4-Chloro-2-fluorophenyl)-8-oxooctanoic acid (CAS 951889-65-9)
- Ethyl 6-(2-chloro-6-fluorophenyl)-6-oxohexanoate (CAS 951887-11-9)
- 1-(4-(1H-Indol-1-yl)phenyl)ethanone (CAS 25700-07-6)
- 3-(2-(O-tolyl)hydrazono)piperidin-2-one (CAS 14490-03-0)
- 2-(5-Bromo-2-oxopyridin-1(2h)-yl)-N-(1h-pyrazol-4-yl)acetamide (CAS 1153939-37-7)
- 4-Methylphenacyl thiocyanate (CAS 6097-27-4)
- (5-Hydroxy-3,4,4,5-tetramethyl-4,5-dihydro-1H-pyrazol-1-yl)(p-tolyl)methanone (CAS 87885-63-0)
- 2-(4-(3-Chlorophenyl)piperazin-1-yl)-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acetamide (CAS 329079-95-0)
- Neoastilbin (CAS 54081-47-9)
- (R)-Ranolazine (CAS 114246-80-9)
- 4H-Benzo[4,5]imidazo[1,2-b]pyrazol-3-amine (CAS 197356-50-6)
- (9-D-Asp) Semaglutide X Sodium salt (CAS CATO-CPTD788617)
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