Ethyl 2-(2-chloroacetamido)-4-cyclopropylthiophene-3-carboxylate CAS 735319-21-8

Description

Compared with other compounds in its class, the molecular weight of 287.76 g/mol gives Ethyl 2-(2-chloroacetamido)-4-cyclopropylthiophene-3-carboxylate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Ethyl 2-(2-chloroacetamido)-4-cyclopropylthiophene-3-carboxylate (CAS 735319-21-8) is a high-purity analytical reference standard with the molecular formula C12H14ClNO3S and a molecular weight of 287.76 g/mol.

Ethyl 2-(2-chloroacetamido)-4-cyclopropylthiophene-3-carboxylate (C12H14ClNO3S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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