1-(2-Chlorophenyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid CAS 449797-42-6
| CAS No. | 449797-42-6 |
| Molecular Formula | C18H15ClN2O2 |
| Molecular Weight | 326.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(2-Chlorophenyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid.
CATO supplies 1-(2-Chlorophenyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid (CAS 449797-42-6), a certified reference material (molecular formula C18H15ClN2O2, MW 326.78 g/mol) for analytical method development and quality control.
1-(2-Chlorophenyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid (C18H15ClN2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(2-Chlorophenyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H15ClN2O2 |
| Molecular Weight | 326.78 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorophenyl Standards
- 3-(3-(4-Chlorophenyl)-1-phenyl-1H-pyrazol-4-yl)propanoic acid (CAS 108446-79-3)
- Methyl 3-(4-Chlorophenyl)-1-m-tolyl-1H-pyrazole-5-carboxylate (CAS 1202031-50-2)
- Methyl 5-(4-chlorophenyl)-1-(4-methylphenyl)-1H-pyrazole-3-carboxylate (CAS 158941-37-8)
- (2E)-1-[3-(4-Chlorophenyl)-2,1-benzoxazol-5-yl]-3-(dimethylamino)prop-2-en-1-one (CAS 337920-27-1)
- (3-(2-Chlorophenyl)-5-methylisoxazol-4-yl)-N-benzylformamide (CAS 300377-64-4)
- 1-((3-(4-Chlorophenyl)-2-hydroxynaphthalen-1-yl)methyl)urea (CAS 901762-40-1)
- 1-(3-(4-Chlorophenyl)acryloyl)-5-phenylpyrazolidin-3-one (CAS 821773-10-8)
- 1-(4-Chlorophenyl)-5-methyl-N-(p-tolyl)-1H-1,2,4-triazole-3-carboxamide (CAS 321431-25-8)
Recommended Standards
- (E)-N'-{7-[(Z)-2-(4-chlorophenyl)ethenyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}-N,N-dimethylmethanimidamide (CAS 303145-86-0)
- 2-(3-(4-Chlorophenyl)-1-(m-tolyl)-1H-pyrazol-4-yl)acetic acid (CAS 55432-13-8)
- 2-(4-(6-Chloropyridin-2-yl)piperazin-1-yl)-1-(4-hydroxyisoxazolidin-2-yl)ethan-1-one (CAS 344276-42-2)
- 2-(4-Chlorophenyl)-6,6-dimethyl-4,8-dioxospiro[2.5]octane-1,1-dicarbonitrile (CAS 477890-29-2)
- 2-((tert-Butyldimethylsilyl)ethynyl)pinacol borate (CAS 1073355-02-8)
- 6,7-Dimethoxy-N-[(2-methoxyphenyl)methyl]quinazolin-4-amine (CAS 672952-05-5)
- 3-ethyl-4,5-dihydro-1,2-oxazole-5-carboxylic acid 471246-96-5 Z2106602829 (CAS 471246-96-5)
- 6-Iodo-N,N-dimethylpyrazin-2-amine (CAS 125060-66-4)
- 8-Chloro-3-isopropyl-2-methylquinolin-4-ol (CAS 1344239-38-8)
- 4-(Cyclohexyloxy)aniline hydrochloride (CAS 105971-50-4)
- 6-Amino-2-(2-(diethylamino)ethyl)-5-methoxy-1H-benzo[de]isoquinoline-1,3(2H)-dione (CAS 81197-88-8)
- 5-methyl-1-(propan-2-yl)-1H-pyrazol-3-ol (CAS 921212-81-9)
- 5-Chloro-2-(5-nitrofuran-2-yl)benzofuran (CAS 89266-53-5)
- Des-Ala35-Tirzepatide (CAS CATO-CPTD788939)
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