6-(2,4-Difluorophenoxy)-8-methyl-2-(methylsulfonyl)pyrido[2,3-d]pyrimidin-7(8H)-one CAS 449808-50-8
| CAS No. | 449808-50-8 |
| Molecular Formula | C15H11F2N3O4S |
| Molecular Weight | 367.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 6-(2,4-Difluorophenoxy)-8-methyl-2-(methylsulfonyl)pyrido[2,3-d]pyrimidin-7(8H)-one is closely related to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
6-(2,4-Difluorophenoxy)-8-methyl-2-(methylsulfonyl)pyrido[2,3-d]pyrimidin-7(8H)-one (CAS 449808-50-8), molecular formula C15H11F2N3O4S and molecular weight 367.33 g/mol, is a CATO reference standard with documented purity and traceability.
6-(2,4-Difluorophenoxy)-8-methyl-2-(methylsulfonyl)pyrido[2,3-d]pyrimidin-7(8H)-one (C15H11F2N3O4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 6-(2,4-Difluorophenoxy)-8-methyl-2-(methylsulfonyl)pyrido[2,3-d]pyrimidin-7(8H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H11F2N3O4S |
| Molecular Weight | 367.33 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Difluorophenoxy Standards
- 4-[6-(2,4-Difluorophenoxy)-2-phenylpyrimidin-4-yl]morpholine (CAS 478067-70-8)
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Recommended Standards
- Picoxystrobin (CAS 117428-22-5)
- Ethyl 5-(1-ethyl-3-methyl-1H-pyrazol-4-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylate (CAS 512814-13-0)
- Naphthalen-2-yl(1-(4-(trifluoromethyl)phenyl)-1H-1,2,3-triazol-4-yl)methanone (CAS 866149-78-2)
- tert-Butyl 2,2,6,6-tetramethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate (CAS 2716848-74-5)
- 2-(2-Methoxypropan-2-yl)aniline (CAS 2844382-97-2)
- 1-Methyl-4-(4-fluoroÂphenylÂ)-piperidine-3-carboxyÂlic acid L-menthyl ester (CAS 627098-37-7)
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- 1-(Benzo[d]thiazol-5-yl)ethanamine hydrochloride (CAS 916162-91-9)
- 2-(2-(4-(4-Fluorophenyl)piperazin-1-yl)-2-oxoethyl)isoindoline-1,3-dione (CAS 53646-64-3)
- 2-(3-(Aminomethyl)piperidin-1-yl)-N-butylacetamide (CAS 1247044-70-7)
- Butyl Benzenesulfonate (CAS 80-44-4)
- 3-(Thiophen-2-yl)-2-(p-tolyl)propanoic acid (CAS 1017189-40-0)
- Palmitoyl Hexapeptide-12 TFA salt (CAS 171263-26-6(Free Base))
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