2-((Furan-2-ylmethyl)amino)-6-methylpyrimidin-4(3H)-one CAS 451523-59-4
| CAS No. | 451523-59-4 |
| Molecular Formula | C10H11N3O2 |
| Molecular Weight | 205.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-((Furan-2-ylmethyl)amino)-6-methylpyrimidin-4(3H)-one.
2-((Furan-2-ylmethyl)amino)-6-methylpyrimidin-4(3H)-one (CAS 451523-59-4) is a high-purity analytical reference standard with the molecular formula C10H11N3O2 and a molecular weight of 205.21 g/mol.
2-((Furan-2-ylmethyl)amino)-6-methylpyrimidin-4(3H)-one (C10H11N3O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H11N3O2 |
| Molecular Weight | 205.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
Related Furan Standards
- n-[(furan-2-yl)methyl]-2-methylfuran-3-carboxamide (CAS 117534-38-0)
- 2-((6-(Furan-2-yl)pyridazin-3-yl)oxy)ethan-1-amine (CAS 1283108-34-8)
- n-(Furan-2-ylmethyl)-4-methoxypyrimidin-2-amine (CAS 1311762-31-8)
- 5-(Furan-2-yl)-3-(pyrrolidin-3-yl)-1,2,4-oxadiazole (CAS 1402672-64-3)
- N-(2-(Furan-3-yl)ethyl)furan-2-carboxamide (CAS 1428355-30-9)
- (2Z)-2-[(Furan-2-yl)methylidene]-1-azabicyclo[2.2.2]octan-3-ol (CAS 866138-54-7)
- n-(Furan-2-ylmethyl)-1-(5-methylfuran-2-yl)ethan-1-amine (CAS 953745-26-1)
- N-(Furan-2-ylmethyl)cyclohex-3-ene-1-carboxamide (CAS 2034352-68-4)
Recommended Standards
- 2-((Cyclopropylamino)carbonyl)benzoic acid (CAS 716362-51-5)
- 2-(1H-Benzo[d][1,2,3]triazol-1-yl)-2-methylpropanoic acid (CAS 4233-61-8)
- 2-((3-Phenyl-1,2,4-oxadiazol-5-yl)amino)ethanol (CAS 7627-09-0)
- 2-(1-Hydroxypropan-2-yl)isoindoline-1,3-dione (CAS 211501-36-9)
- 2-(2,4-Difluorophenyl)imidazo[1,2-a]pyridine (CAS 769093-92-7)
- 2,3',4',5-Tetrachlorobiphenyl-3,4,6-d3 (CAS 1219794-77-0)
- 3-((5-Methyl-1h-benzo[d]imidazol-2-yl)thio)propanal (CAS 1342420-61-4)
- Methyl 5-(1-(2-chlorophenyl)-3-(ethoxycarbonyl)-1H-pyrazol-4-yl)-3-(2,6-dichlorophenyl)isoxazole-4-carboxylate (CAS 321571-33-9)
- Ethyl 2-amino-4-(furan-2-yl)thiophene-3-carboxylate (CAS 256506-99-7)
- 2-(4-Piperidylmethyl)thiazole (CAS 1017163-98-2)
- 7-Bromo-9-chloro-2-ethyl-4H-pyrido[1,2-a]pyrimidin-4-one (CAS 2275753-30-3)
- 7-[3-(Trifluoromethyl)pyridin-2-yl]quinazolin-4-ol (CAS 573675-81-7)
- 8-Oxoundecanoic acid (CAS 91214-06-1)
- Semaglutide impurity 205 (CAS CATO-C4X-2226205)
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