2-Fluoro-5-iodotoluene CAS 452-68-6

Purity 97%+In StockPharmaceutical Standards
CAS No.452-68-6
Molecular FormulaC7H6FI
Molecular Weight236.03 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Fluoro-5-iodotoluene CAS 452-68-6 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 236.03 g/mol gives 2-Fluoro-5-iodotoluene distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 2-Fluoro-5-iodotoluene (CAS 452-68-6), a certified reference material (molecular formula C7H6FI, MW 236.03 g/mol) for analytical method development and quality control.

The molecular framework of 2-Fluoro-5-iodotoluene (C7H6FI) is characterized by fluorine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC7H6FI
Molecular Weight236.03 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Halogen ContentF/I-containing

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