2-(2-((2-Chloro-7-methylquinolin-3-yl)methylene)hydrazinyl)-3-(o-tolyl)quinazolin-4(3H)-one CAS 327039-01-0
| CAS No. | 327039-01-0 |
| Molecular Formula | C26H20ClN5O |
| Molecular Weight | 453.92 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 453.92 g/mol gives 2-(2-((2-Chloro-7-methylquinolin-3-yl)methylene)hydrazinyl)-3-(o-tolyl)quinazolin-4(3H)-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-(2-((2-Chloro-7-methylquinolin-3-yl)methylene)hydrazinyl)-3-(o-tolyl)quinazolin-4(3H)-one (CAS 327039-01-0) is a high-purity analytical reference standard with the molecular formula C26H20ClN5O and a molecular weight of 453.92 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 2-(2-((2-Chloro-7-methylquinolin-3-yl)methylene)hydrazinyl)-3-(o-tolyl)quinazolin-4(3H)-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 453.92 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(2-((2-Chloro-7-methylquinolin-3-yl)methylene)hydrazinyl)-3-(o-tolyl)quinazolin-4(3H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C26H20ClN5O |
| Molecular Weight | 453.92 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Chloro Standards
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Recommended Standards
- (E)-{[4-(4-chlorophenyl)-7-thia-2,5-diazatricyclo[6.4.0.0^{2,6}]dodeca-1(8),3,5-trien-3-yl]methylidene}amino 4-fluorobenzoate (CAS 478041-89-3)
- Halobetasol Impurity 9 (CAS CATO-C4X-33149)
- Flumetasone Impurity 14 (CAS 3873-19-6)
- N-[(2-Chlorophenyl)methyl]-2-{[3-cyano-6-methyl-4-(trifluoromethyl)-5,6,7,8-tetrahydroquinolin-2-yl]sulfanyl}acetamide (CAS 626228-72-6)
- 3,4-Bis(4-methoxyphenyl)isoxazole (CAS 138584-27-7)
- 3-Chloro-2-(trifluoromethyl)aniline (CAS 432-21-3)
- 4-(Isobutyryl)benzoic acid (CAS 32018-30-7)
- 2-(3,4-Dichlorobenzoyl)-5-(1,3-dioxolan-2-yl)thiophene (CAS 898778-94-4)
- H-Leu-Trp-Met-Arg-Phe-OH (CAS 67201-39-2)
- Trifarotene Impurity 7 (CAS 895543-08-5)
- Nor-Binaltorphimine dihydrochloride (CAS 113158-34-2)
- Ammonium lauryl sulfate (CAS 68081-96-9)
- (4-((1H-Benzo[d]imidazol-2-yl)methyl)piperazin-1-yl)(thiophen-2-yl)methanone (CAS 1172356-10-3)
- Allo-Thr5-Tirzepatide (CAS CATO-CPTD788934)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com