3-(Trifluoromethyl)anisole CAS 454-90-0
| CAS No. | 454-90-0 |
| Molecular Formula | C8H7F3O |
| Molecular Weight | 176.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(Trifluoromethyl)anisole.
CATO supplies 3-(Trifluoromethyl)anisole (CAS 454-90-0), a certified reference material (molecular formula C8H7F3O, MW 176.14 g/mol) for analytical method development and quality control.
The molecular framework of 3-(Trifluoromethyl)anisole (C8H7F3O) is characterized by a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-(Trifluoromethyl)anisole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H7F3O |
| Molecular Weight | 176.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Trifluoromethyl Standards
- 2-Methyl-5-(trifluoromethyl)phenol (CAS 1017778-05-0)
- 4-Methyl-3-(trifluoromethyl)phenol (CAS 1017778-16-3)
- (3-(Trifluoromethyl)pyridin-4-yl)methanamine (CAS 1060801-91-3)
- 3-Methyl-2-(trifluoromethyl)phenol (CAS 106877-37-6)
- 5-Methyl-2-(trifluoromethyl)phenol (CAS 106877-38-7)
- 3-Methyl-4-(trifluoromethyl)phenol (CAS 106889-91-2)
- 3-Methyl-5-(trifluoromethyl)pyridin-4-amine (CAS 1101061-18-0)
- 4-Methyl-2-(trifluoromethyl)pyridin-3-amine (CAS 1211540-24-7)
Recommended Standards
- 3-(Trifluoromethyl)-1,4,5,6-tetrahydrocyclopenta[c]pyrazole (CAS 347361-46-0)
- 3-(Trifluoromethyl)benzene-1,2-diamine (CAS 360-60-1)
- 3-(Aminomethyl)-6-(trifluoromethyl)pyridine (CAS 387350-39-2)
- 3-Amino-2-methyl-6-(trifluoromethyl)pyridine (CAS 383907-17-3)
- 5-Fluoro-2-(trimethylstannyl)pyridine (CAS 453568-60-0)
- 1,2,3,4-Tetrahydrobenzofuro[3,2-c]pyridine (CAS 43213-61-2)
- 2-(2,5-Dichlorophenyl)-1H-benzo[d]imidazole (CAS 14225-80-0)
- 3-(3-Fluorophenyl)isothiazole-5-carboxylic acid (CAS 1338689-93-2)
- 1-Methyl-5-phenyl-1H-pyrazole-4-carbaldehyde (CAS 154927-01-2)
- rel-4,4,5,5-Tetramethyl-2-[(1R,2R)-2-phenylcyclopropyl]-1,3,2-dioxaborolane (CAS 749885-71-0)
- 6-Methyl-2-(3-oxo-3H-benzo[f]chromene-2-carboxamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide hydrochloride (CAS 1330295-32-3)
- 3-Cyano-5-nitrobenzoic acid (CAS 98556-65-1)
- Hexahydro-1H-inden-5(6H)-one (CAS 5686-84-0)
- Neuropeptide GE (CAS 134748-04-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com