Fluvoxamine Impurity 23 CAS 455-18-5
| CAS No. | 455-18-5 |
| Molecular Formula | C8H4F3N |
| Molecular Weight | 171.12 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Fluvoxamine Impurity 23 (CAS 455-18-5) is a certified pharmaceutical impurity reference standard with the molecular formula C8H4F3N and a molecular weight of 171.12 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, Fluvoxamine Impurity 23 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 171.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H4F3N |
| Molecular Weight | 171.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluvoxamine Standards
- Fluvoxamine Impurity 32 (CAS 34008-70-3)
- Fluvoxamine Impurity N1 (CAS 1391053-78-3)
- Fluvoxamine Impurity 28 (CAS CATO-C4X-195128)
- Fluvoxamine Impurity 27 (CAS CATO-C4X-195127)
- Fluvoxamine impurity 42 (CAS CATO-C4X-195142)
- Fluvoxamine Impurity 53 (CAS CATO-C4X-195153)
- Fluvoxamine EP Impurity D (CAS 61718-80-7)
- Fluvoxamine Impurity 15 (CAS 61718-83-0)
Recommended Standards
- 3-(Trifluoromethyl)benzonitrile (CAS 368-77-4)
- 2,4,5-Trifluorophenylacetonitrile (CAS 220141-74-2)
- 2,3,5-TRIFLUOROBENZYL CYANIDE 2,3,5-TRIFLUOROPHENYLACETIC ACID 2,3,5-TRIFLUOROPHENYLACETONITRILE 2,4,6-Trifluorophenylacetonitrile 2-(2,3,5-TRIFLUOROPHENYL)ACETONITRILE 243666-14-0 AS01981 RARECHEM AL BO 0711 (CAS 243666-14-0)
- 5-Amino-2-fluoro-3-hydroxybenzoic acid (CAS 1025127-32-5)
- Desoximetasone Impurity 4 (CAS CATO-C4X-16094)
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- Peramivir Impurity 79 (CAS CATO-C4X-183379)
- Ethyl 4-(butylsulfanyl)-6-oxo-1-phenyl-1,6-dihydropyridazine-3-carboxylate (CAS 339031-45-7)
- 1-Ethyl-2,3-dimethyl-1H-indole-5-carboxylic acid (CAS 438218-59-8)
- 3-(Furan-3-yl)morpholine (CAS 1270581-58-2)
- 4-Amino-1-(cyclopropylmethyl)pyrrolidin-2-one (CAS 1155572-93-2)
- 7-Methyl-2,5-dioxo-1,2,5,6,7,8-hexahydroquinoline-3-carboxylic acid (CAS 106551-77-3)
- 1-(5-Bromo-6-methylpyridin-2-yl)-4-methylpiperazine (CAS 1454301-28-0)
- Des-[Oct-γ-Glu-AEEA-AEEA]-Semaglutide (CAS CATO-C4X-2226112)
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