Methyl (S)-2-amino-3-(4-ethoxyphenyl)propanoate hydrochloride CAS 4557-01-1
| CAS No. | 4557-01-1 |
| Molecular Formula | C12H17NO3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl (S)-2-amino-3-(4-ethoxyphenyl)propanoate hydrochloride.
Methyl (S)-2-amino-3-(4-ethoxyphenyl)propanoate hydrochloride (CAS 4557-01-1), molecular formula C12H17NO3HCl and molecular weight 259.73 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Methyl (S)-2-amino-3-(4-ethoxyphenyl)propanoate hydrochloride is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 259.73 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H17NO3 HCl |
| Molecular Weight | 259.73 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 4-(2-Acetamidoethyl)-3-iodobenzoic acid (CAS 1131622-45-1)
- 4-ethyl-2-[(piperazin-1-yl)methyl]morpholine (CAS 1354951-63-5)
- 2-chloro-4-methoxy-3-nitro-pyridine (CAS 6980-09-2)
- (2-Amino-6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-3-yl)(4-ethoxyphenyl)methanone (CAS 890092-92-9)
- 2-(1-Trityl-4-imidazolyl)benzaldehyde (CAS 1402838-08-7)
- 4-(tert-Butoxy)phenol (CAS 301353-98-0)
- (1H-Indol-3-yl)dimethylphosphine oxide (CAS 2577446-81-0)
- 0825AE 3-(Benzyloxy)-N-methylaniline 33905-38-3 C14H15NO (CAS 33905-38-3)
- Roxadustat Impurity 54 (CAS CATO-C4X-221354)
- D-Ile27-Tirzepatide (CAS CATO-CPTD788907)
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