1-Fluoro-4-(fluoromethyl)benzene CAS 459-51-8
| CAS No. | 459-51-8 |
| Molecular Formula | C7H6F2 |
| Molecular Weight | 128.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-Fluoro-4-(fluoromethyl)benzene (CAS 459-51-8) is a high-purity analytical reference standard with the molecular formula C7H6F2 and a molecular weight of 128.12 g/mol.
Owing to fluorine substitution, an aromatic ring system, 1-Fluoro-4-(fluoromethyl)benzene is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 128.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-Fluoro-4-(fluoromethyl)benzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H6F2 |
| Molecular Weight | 128.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Fluoro Standards
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Recommended Standards
- 2,3-Difluorotoluene (CAS 3828-49-7)
- (Trifluoromethyl)(vinyl)sulfane (CAS 762-80-1)
- 2,4-Difluorotoluene (CAS 452-76-6)
- 2-hydroxyethane-1-sulfonyl fluoride (CAS 1893924-11-2)
- 3-Methyl-4-phenylbutan-2-yl acetate (CAS 34362-37-3)
- Pirfenidone-d5 (5-Methyl-N-Phenyl-2-1H-Pyridone-d5) (CAS 1020719-62-3)
- Benzyl 2-Acetamido-2-deoxy-4-O-(b-D-galactopyranosyl)-b-D-glucopyranoside (CAS 53167-38-7)
- Hexestrol (CAS 84-16-2)
- (D-Pro7)-Angiotensin I/II (1-7) (CAS 586962-44-9)
- 2,6-Diaminopyrimidine-4-carbaldehyde (CAS 109138-03-6)
- (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-cyanobutanoic acid (CAS 913253-24-4)
- (S)-N-Boc-2-aminomethylmorpholine (CAS 879403-42-6)
- Acridine-1-carbonitrile (CAS 42978-64-3)
- Tirzepatide Impurity 16 (CAS CATO-C4X-324016)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com