1-Bromo-4-(fluoromethyl)benzene CAS 459-49-4
| CAS No. | 459-49-4 |
| Molecular Formula | C7H6BrF |
| Molecular Weight | 189.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 189.02 g/mol gives 1-Bromo-4-(fluoromethyl)benzene distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 1-Bromo-4-(fluoromethyl)benzene (CAS 459-49-4), a certified reference material (molecular formula C7H6BrF, MW 189.02 g/mol) for analytical method development and quality control.
Based on its molecular formula C7H6BrF, 1-Bromo-4-(fluoromethyl)benzene contains fluorine/bromine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 189.02 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H6BrF |
| Molecular Weight | 189.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 2-Bromo-4-fluorotoluene (CAS 1422-53-3)
- 2-Bromo-6-fluorotoluene (CAS 1422-54-4)
- 1-Bromo-2-(fluoromethyl)benzene (CAS 446-47-9)
- 1-Bromo-3-(fluoromethyl)benzene (CAS 456-43-9)
- 2-Bromo-3-fluorotoluene (CAS 59907-13-0)
- 3-Bromo-4-fluorotoluene (CAS 452-62-0)
- 3-Bromo-5-fluorotoluene (CAS 202865-83-6)
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- (E)-5-(((4-Chlorobenzylidene)amino)methyl)-2-methylpyrimidin-4-amine (CAS 20352-46-9)
- 4-Bromo-5-methylpicolinamide (CAS 1823882-81-0)
- Ethyl 2-(N-(4-bromophenyl)-2-morpholinoacetamido)acetate (CAS 332128-45-7)
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