2,6-Bis(trifluoromethyl)phenol CAS 46377-35-9

Purity 97%+In StockPharmaceutical Standards
CAS No.46377-35-9
Molecular FormulaC8H4F6O
Molecular Weight230.11 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2,6-Bis(trifluoromethyl)phenol CAS 46377-35-9 chemical structure

Description

2,6-Bis(trifluoromethyl)phenol (C8H4F6O) contains a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

2,6-Bis(trifluoromethyl)phenol (CAS 46377-35-9) is a high-purity analytical reference standard with the molecular formula C8H4F6O and a molecular weight of 230.11 g/mol.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC8H4F6O
Molecular Weight230.11 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1970
Halogen ContentF-containing

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