rel-(1R,2S)-2-Fluoro-2-phenylcyclopropanamine hydrochloride CAS 465547-34-6
| CAS No. | 465547-34-6 |
| Molecular Formula | C9H10FN |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of rel-(1R,2S)-2-Fluoro-2-phenylcyclopropanamine hydrochloride (C9H10FNHCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
rel-(1R,2S)-2-Fluoro-2-phenylcyclopropanamine hydrochloride (CAS 465547-34-6) is a high-purity analytical reference standard with the molecular formula C9H10FNHCl and a molecular weight of 187.64 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), rel-(1R,2S)-2-Fluoro-2-phenylcyclopropanamine hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H10FN HCl |
| Molecular Weight | 187.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- (4-Chloropyridin-3-yl)methanamine;hydrochloride (CAS 1956319-15-5)
- 1-[4-(propan-2-yl)phenyl]propan-1-amine (CAS 832741-12-5)
- Thiazolo[3,2-a]indole-9-carboxylic acid (CAS 152812-49-2)
- 2-Bromo-4,5,6,7-tetrahydrothieno[3,2-c]pyridine hydrobromide (CAS 733757-75-0)
- 4-azatricyclo[4.2.1.0³⁷]nonan-2-ol (CAS 1552375-92-4)
- Faropenem Impurity 92 (CAS 171890-81-6)
- Acipimox Impurity 14 (CAS 98006-89-4)
- 2-((6-Chloropyrazin-2-yl)thio)acetic acid (CAS 884497-52-3)
- 3-(Cyclopropylmethoxy)-5-hydroxybenzonitrile (CAS 1243456-83-8)
- Acetyl Hexapeptide-39 (CAS 1382088-38-1)
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