Acipimox Impurity 14 CAS 98006-89-4
| CAS No. | 98006-89-4 |
| Molecular Formula | C8H10N2O2 |
| Molecular Weight | 166.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Acipimox Impurity 14 (CAS 98006-89-4, C8H10N2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Acipimox Impurity 14 (C8H10N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Acipimox Impurity 14 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H10N2O2 |
| Molecular Weight | 166.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 2 |
Related Acipimox Standards
Recommended Standards
- Nikethamide Impurity 3 (CAS 68254-63-7)
- Thiamine /Vitamin B1 Impurity 18 (CAS 1886-34-6)
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- Calcium Folinate EP Impurity B (Mixture of Diastereomers) (CAS 98814-60-9)
- Fenofibrate Impurity 34 (CAS 258834-37-6)
- N-nitroso Rifamycin Impurity 17 (CAS CATO-C4X-200417)
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- 6-Methoxy-3-phenyl-3H-imidazo[4,5-b]pyridin-5-ol (CAS 1956376-95-6)
- ethyl 4-(cyclopropylamino)-2-(methylthio)pyrimidine-5-carboxylate (CAS 651734-65-5)
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- 6-Methyl-1H-indole-4-carboxamide (CAS 2169612-33-1)
- Cholecystokinin Octapeptide (desulfated) (H-2070.0005) (CAS 198483-36-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com