1-(2-amino-4-chloro-3-fluoro-phenyl)-2-chloro-ethanone CAS 467456-99-1

Purity 97%+In StockPharmaceutical Standards
CAS No.467456-99-1
Molecular FormulaC8H6Cl2FNO
Molecular Weight222.04 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(2-amino-4-chloro-3-fluoro-phenyl)-2-chloro-ethanone CAS 467456-99-1 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 222.04 g/mol gives 1-(2-amino-4-chloro-3-fluoro-phenyl)-2-chloro-ethanone distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 1-(2-amino-4-chloro-3-fluoro-phenyl)-2-chloro-ethanone (CAS 467456-99-1), a certified reference material (molecular formula C8H6Cl2FNO, MW 222.04 g/mol) for analytical method development and quality control.

The molecular framework of 1-(2-amino-4-chloro-3-fluoro-phenyl)-2-chloro-ethanone (C8H6Cl2FNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

As a certified reference material (CRM), 1-(2-amino-4-chloro-3-fluoro-phenyl)-2-chloro-ethanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H6Cl2FNO
Molecular Weight222.04 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF/Cl-containing
Nitrogen Atoms1

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