(5-(2-Fluorophenyl)thiophen-2-yl)boronic acid CAS 2122282-68-0
| CAS No. | 2122282-68-0 |
| Molecular Formula | C10H8BFO2S |
| Molecular Weight | 222.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
(5-(2-Fluorophenyl)thiophen-2-yl)boronic acid (CAS 2122282-68-0), molecular formula C10H8BFO2S and molecular weight 222.04 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, (5-(2-Fluorophenyl)thiophen-2-yl)boronic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 222.04 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures (5-(2-Fluorophenyl)thiophen-2-yl)boronic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H8BFO2S |
| Molecular Weight | 222.04 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Fluorophenyl Standards
- (4-(2-Fluorophenyl)thiophen-2-yl)boronic acid (CAS 2225155-39-3)
- (4-(3-Fluorophenyl)thiophen-2-yl)boronic acid (CAS 2225170-24-9)
- (4-(4-Fluorophenyl)thiophen-2-yl)boronic acid (CAS 2225169-65-1)
- 2-(4-Fluorophenyl)-4,4,6-trimethyl-1,3,2-dioxaborinane (CAS 1029653-69-7)
- 1-(4-Fluorophenyl)-2-(trifluoromethoxy)ethan-1-one (CAS 1334146-77-8)
- 1-(3-Fluorophenyl)-2-(trifluoromethoxy)ethan-1-one (CAS 1334148-55-8)
- 1-[(4-Fluorophenyl)methyl]imidazolidine-2,4,5-trione (CAS 105686-00-8)
- 1-(3-Fluorophenyl)-4-hydroxy-1h-pyrazole-3-carboxylic acid (CAS 1152511-49-3)
Recommended Standards
- (4-(5-Fluorothiophen-2-yl)phenyl)boronic acid (CAS 662142-08-7)
- (5S,6R)-4-Amino-5-bromo-6-hydroxy-1-methyl-5,6-dihydropyrimidin-2(1H)-one (CAS 734489-50-0)
- 1-(2-amino-4-chloro-3-fluoro-phenyl)-2-chloro-ethanone (CAS 467456-99-1)
- 2-Bromo-1H-pyrrolo[2,3-b]pyridine-6-carbonitrile (CAS 2092825-87-9)
- ((1-Hydroxycyclohexyl)methyl)diphenylphosphine oxide (CAS 87512-43-4)
- Tert-butyl 5-amino-4-cyano-1H-pyrazole-1-carboxylate (CAS 1232792-00-5)
- 3-(4-(Benzyloxy)-3-methoxybenzylidene)-5-(3,4-dimethoxyphenyl)furan-2(3H)-one (CAS 7153-97-1)
- 6-(Aminomethyl)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-ol (CAS 882252-36-0)
- S-(2-Chloro-2-propen-1-yl) ethanethioate (CAS 24891-77-8)
- 2,2'-((2-((2-(Benzylcarbamoyl)phenoxy)methyl)-2-methylpropane-1,3-diyl)bis(oxy))bis(n-benzylbenzamide) (CAS 438457-74-0)
- 1-Methylamino-1-phenylpropane hydrochloride (CAS 76605-79-3)
- 2,4,5-T-2-Butoxy Isopropyl Ester (CAS CATO-CCEM500174)
- 4-(2-Methylpyridin-4-yl)-1H-imidazol-5-amine (CAS 851262-41-4)
- Semaglutide Impurity 184 (CAS CATO-C4X-2226184)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com