6-Chloropicolinic acid CAS 4684-94-0
| CAS No. | 4684-94-0 |
| Molecular Formula | C6H4ClNO2 |
| Molecular Weight | 157.55 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 6-Chloropicolinic acid (CAS 4684-94-0), a certified reference material (molecular formula C6H4ClNO2, MW 157.55 g/mol) for analytical method development and quality control.
6-Chloropicolinic acid (C6H4ClNO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H4ClNO2 |
| Molecular Weight | 157.55 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloropicolinic Standards
Recommended Standards
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- 6-Chloronicotinic Acid (CAS 5326-23-8)
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- 6-(4-Chlorophenyl)-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile (CAS 69538-75-6)
- 3-[(2,6-Dichlorophenyl)methyl]-1-[(4-methoxyphenyl)methyl]-2-methyl-1,4-dihydropyridin-4-one (CAS 339017-32-2)
- N-methyl-N-[(2-propoxy-1-naphthyl)methyl]amine (CAS 851116-62-6)
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- 4,4-Diethyl-3-hydroxydihydrofuran-2(3H)-one (CAS 222609-29-2)
- Fluralaner Impurity 27 (CAS CATO-C4X-218027)
- Semaglutide impurity 63 (CAS CATO-C4X-222663)
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