Sorafenib Impurity 45 CAS 46843-47-4
| CAS No. | 46843-47-4 |
| Molecular Formula | C13H14N2O2 |
| Molecular Weight | 230.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Sorafenib Impurity 45 (CAS 46843-47-4, C13H14N2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C13H14N2O2, Sorafenib Impurity 45 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 230.26 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Sorafenib Impurity 45 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H14N2O2 |
| Molecular Weight | 230.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1970 |
| Nitrogen Atoms | 2 |
Related Sorafenib Standards
- Sorafenib Impurity 30 (CAS 1012058-77-3)
- Sorafenib Impurity 59 (CAS 284462-80-2)
- Sorafenib Impurity 10 (CAS 2004659-85-0)
- Sorafenib Impurity 21 (CAS CATO-C4X-112421)
- Sorafenib Impurity 57 (CAS 656-96-2)
- Sorafenib Impurity 12 (CAS 343247-69-8)
- Sorafenib Impurity 15 (CAS CATO-C4X-112415)
- Sorafenib Impurity 32 (CAS 50528-86-4)
Recommended Standards
- Edaravone impurity 32 (CAS 852539-02-7)
- Sitafloxacin Impurity 49 (CAS 129306-06-5)
- 4-Benzyloxy-3-methoxyphenol (CAS 40232-88-0)
- Bisoprolol Impurity 56 (CAS 145059-66-1)
- Olodaterol Impurity 16 (CAS CATO-C4X-194316)
- Salbutamol Impurity 109 (CAS CATO-C4X-1176109)
- Arginine Impurity 5 (CAS 28958-90-9)
- (S)-2-(3-Hydroxypyridin-2-yl)-4-methyl-4,5-dihydrothiazole-4-carboxylic acid (CAS 76045-30-2)
- 2-(Triphenylstannyl)benzo[d]thiazole (CAS 124187-26-4)
- 6-Oxo-7-oxa-5-azaspiro[3.4]octane-2-carboxylic acid (CAS 2402831-35-8)
- (4-Methoxyphenyl)triphenylsilane (CAS 14311-00-3)
- 5,6,7-trifluoro-2,3-dihydro-1H-inden-1-amine hydrochloride (CAS 1864058-49-0)
- N-(1,1-dioxidotetrahydrothiophen-3-yl)-2-iodoacetamide (CAS 880071-96-5)
- Tirzepatide Impurity 19 X TFA Salt (CAS CATO-C4X-324019)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com