Piperazine Impurity 2 CAS 47159-85-3
| CAS No. | 47159-85-3 |
| Molecular Formula | C18H22N2S |
| Molecular Weight | 298.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Piperazine Impurity 2 (CAS 47159-85-3) is a certified pharmaceutical impurity reference standard with the molecular formula C18H22N2S and a molecular weight of 298.45 g/mol.
The molecular framework of Piperazine Impurity 2 (C18H22N2S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Piperazine Impurity 2 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H22N2S |
| Molecular Weight | 298.45 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1970 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Piperazine Standards
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- Piperazine Impurity 46 (CAS CATO-C4X-242746)
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- Piperazine, 1-(5-bromo-2-nitrophenyl)-4-methyl- (CAS 1219730-40-1)
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Recommended Standards
- Vortioxetine Impurity 56 (CAS CATO-C4X-105656)
- tert-Butyl (2R,5S)-2,5-diisobutylpiperazine-1-carboxylate (CAS 1240582-43-7)
- Vortioxetine Impurity 55 (CAS CATO-C4X-105655)
- tert-Butyl (2R,5R)-2,5-diisobutylpiperazine-1-carboxylate hydrochloride (CAS 1240585-34-5)
- Cefotiam Impurity 19 (CAS CATO-C4X-120419)
- Pantoprazole Impurity 48 (CAS CATO-C4X-139948)
- Dapagliflozin Impurity 208 (CAS CATO-C4X-1138208)
- 5-Methoxy-2-(pyrrolidin-2-yl)pyridine (CAS 1256805-51-2)
- (R)-1-(4,4-Difluoroisochroman-8-yl)ethan-1-amine (CAS 2488795-17-9)
- 5-Bromo-7-(trifluoromethyl)imidazo[1,5-a]pyridine (CAS 2092707-42-9)
- Potassium 2-hydrazono-3-methyl-2,3-dihydrobenzo[d]thiazole-6-sulfonate (CAS 65540-57-0)
- 4-(Benzyloxy)-2-butynoic Acid Methyl Ester (CAS 149125-61-1)
- Magnesium 2-ethoxyethanolate (CAS 14064-03-0)
- Semaglutide Impurity 2 (CAS CATO-C4X-22262)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com