Piperazine Impurity 8 CAS 769083-63-8
| CAS No. | 769083-63-8 |
| Molecular Formula | C19H24N2O |
| Molecular Weight | 296.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Piperazine Impurity 8 (CAS 769083-63-8), a pharmacopoeial impurity reference standard (molecular formula C19H24N2O, MW 296.41 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C19H24N2O, Piperazine Impurity 8 contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 296.41 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Piperazine Impurity 8 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H24N2O |
| Molecular Weight | 296.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 2 |
Related Piperazine Standards
- 1-Boc-4-(piperazine-1-carbonyl)piperidine (CAS 887587-18-0)
- 1,1'-(Piperazine-1,4-diyl)bis(4-chlorobutan-1-one) (CAS 6639-67-4)
- Ethyl 4-(piperazine-1-sulfonyl)benzoate (CAS 737812-97-4)
- Piperazine Impurity 2 (CAS 47159-85-3)
- 4,4'-(Piperazine-1,4-diyl)dibenzaldehyde (CAS 10159-39-4)
- Piperazine Impurity 46 (CAS CATO-C4X-242746)
- Piperazine Impurity 58 (CAS 2088821-92-3)
- Piperazine, 1-(5-bromo-2-nitrophenyl)-4-methyl- (CAS 1219730-40-1)
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- 4-Aminobut-2-yn-1-ol (CAS 63200-68-0)
- 1-Benzyl-1H-indole-6-carbonitrile (CAS 1030423-43-8)
- 1-(4-Bromobenzyl)azetidine (CAS 1044924-69-7)
- (2R,3S,4R,5R,6S)-5-acetamido-2-(acetoxymethyl)-6-(4-bromophenoxy)tetrahydro-2H-pyran-3,4-diyl diacetate (CAS 38229-74-2)
- 2-(6-Chloropyridin-2-yl)-2,3-dihydrobenzo[d][1,3,2]diazaborinin-4(1H)-one (CAS 2242502-35-6)
- Tau Peptide (307-321) trifluoroacetate salt (CAS 330456-50-3)
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