MK-0752 CAS 471905-41-6
| CAS No. | 471905-41-6 |
| Molecular Formula | C21H21ClF2O4S |
| Molecular Weight | 442.90 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of MK-0752 is closely related to a flavonoid core, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies MK-0752 (CAS 471905-41-6), a certified reference material (molecular formula C21H21ClF2O4S, MW 442.90 g/mol) for analytical method development and quality control.
The molecular framework of MK-0752 (C21H21ClF2O4S) is characterized by a flavonoid core, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), MK-0752 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H21ClF2O4S |
| Molecular Weight | 442.90 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Sulfur Atoms | 1 |
Recommended Standards
- Roxadustat Impurity 104 (CAS CATO-C4X-2213104)
- Capivasertib Impurity 12 (CAS CATO-C4X-331212)
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- 2-{[(4-chlorophenyl)methyl]sulfanyl}-5-methoxy-4-{[3-(trifluoromethyl)phenyl]sulfanyl}pyrimidine (CAS 338423-13-5)
- 4-Amino-5-(difluoromethyl)-6-iodonicotinic acid (CAS 1806914-23-7)
- (S)-1-(thiophen-2-yl)pentan-1-amine (CAS 1212815-49-0)
- 2-Oxoindoline-3-carbaldehyde (CAS 78610-70-5)
- 2-Cyclopropoxy-3-sulfamoylbenzoic acid (CAS 1243318-41-3)
- 3-(4-Chloro-2-methylphenyl)piperidine (CAS 1044768-94-6)
- ETHYL 2-AMINO-4-(2-FLUOROPHENYL)THIOPHENE-3-CARBOXYLATE (CAS 849659-32-1)
- 2-Methyl-3-(methylamino)butan-2-ol (CAS 412274-84-1)
- tert-butyl N-[(1S,3S)-3-hydroxycyclopentyl]-N-methylcarbamate (CAS 2165760-01-8)
- N-(tert-butyl)-2-formyl-6-methoxy-N-methylbenzamide (CAS 887585-36-6)
- Semaglutide impurity 42 (CAS CATO-C4X-222642)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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