4-Fluoro-1H-indazole-5-carbonitrile CAS 473416-81-8
| CAS No. | 473416-81-8 |
| Molecular Formula | C8H4FN3 |
| Molecular Weight | 161.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-Fluoro-1H-indazole-5-carbonitrile (CAS 473416-81-8), molecular formula C8H4FN3 and molecular weight 161.14 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C8H4FN3, 4-Fluoro-1H-indazole-5-carbonitrile contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 161.14 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 4-Fluoro-1H-indazole-5-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H4FN3 |
| Molecular Weight | 161.14 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Fluoro Standards
- 4-Fluoro-1H-pyrrolo[2,3-c]pyridine-3-carbonitrile (CAS 1190311-97-7)
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- 6-Fluoro-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile (CAS 1190318-70-7)
- 6-Fluoro-1H-indazole-4-carbonitrile (CAS 1227270-90-7)
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- 4-Fluoro-1H-pyrrolo[2,3-b]pyridine-5-carbonitrile (CAS 1260381-44-9)
- 4-Fluoro-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile (CAS 1260383-56-9)
Recommended Standards
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- TPMPA (CAS 182485-36-5)
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- 1-((1H-Imidazol-1-yl)methyl)-1H-benzo[d]imidazole (CAS 159064-01-4)
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- 1-Azatricyclo[4.2.0.02,4]octane-6-methanol, (2S,4S,6R)- (CAS 2927440-93-3)
- 1-{pyrrolo[2,1-f][1,2,4]triazin-5-yl}ethan-1-one (CAS 1517129-22-4)
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