Atracurium Impurity N8 CAS 4747-98-2
| CAS No. | 4747-98-2 |
| Molecular Formula | C20H25NO4 |
| Molecular Weight | 343.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Atracurium Impurity N8.
CATO supplies Atracurium Impurity N8 (CAS 4747-98-2), a pharmacopoeial impurity reference standard (molecular formula C20H25NO4, MW 343.42 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Atracurium Impurity N8 (C20H25NO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 343.42 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H25NO4 |
| Molecular Weight | 343.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 1 |
Related Atracurium Standards
- Atracurium Impurity 35 (CAS 73841-84-6)
- Atracurium EP Impurity G (CAS 1699-51-0)
- Atracurium Impurity 40 (CAS 109717-73-9)
- Atracurium EP Impurity F (CAS 34866-20-1)
- Atracurium impurity 103 (CAS 872807-64-2)
- Atracurium Impurity 105 (CAS CATO-C4X-1850105)
- Atracurium Impurity 118 (CAS 24734-71-2)
- Atracurium Impurity 75 (CAS CATO-C4X-185075)
Recommended Standards
- R-Tetrahydropapaverine N-acetyl-L-leucinate (CAS 50896-90-7)
- (2R,3R,4S,5S)-2-(6-Amino-9H-purin-9-yl)-5-((((methylthio)methyl)thio)methyl)tetrahydrofuran-3,4-diol (CAS 61839-09-6)
- Sarpogrelate Impurity 10 (CAS CATO-C4X-291310)
- 5-Methyl-3-(((5-(phenoxymethyl)-1H-1,2,4-triazol-3-yl)methyl)thio)isothiazole-4-carbonitrile (CAS 338418-70-5)
- Velpatasvir Impurity 4 (CAS CATO-C4X-28944)
- Ceftaroline Impurity 2 (CAS 700803-62-9)
- Lisinopril EP Impurity C (CAS 328385-86-0)
- 1-Methyl-1H-imidazo[4,5-b]pyridin-2-amine (CAS 178885-60-4)
- 6,7-Dibromo-4-methoxy-1H-indole (CAS 158920-11-7)
- 2-(1H-Benzo[d]imidazol-2-yl)pyridin-4-amine (CAS 1082192-60-6)
- 4-(((3-Nitrophenyl)amino)methyl)phenol (CAS 13159-77-8)
- 1-(4-chloro-2-fluorophenyl)prop-2-yn-1-ol (CAS 1592279-38-3)
- 2-(4-Hydroxy-6-(phenylthio)isoquinoline-3-carboxamido)acetic acid (CAS 808116-39-4)
- MOTS-c Peptide (CAS 1627580-64-6)
Why CATO?
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