6-(Hydroxymethyl)-2-(methylthio)nicotinonitrile CAS 474823-68-2
| CAS No. | 474823-68-2 |
| Molecular Formula | C8H8N2OS |
| Molecular Weight | 180.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 180.23 g/mol gives 6-(Hydroxymethyl)-2-(methylthio)nicotinonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
6-(Hydroxymethyl)-2-(methylthio)nicotinonitrile (CAS 474823-68-2) is a high-purity analytical reference standard with the molecular formula C8H8N2OS and a molecular weight of 180.23 g/mol.
The molecular framework of 6-(Hydroxymethyl)-2-(methylthio)nicotinonitrile (C8H8N2OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 6-(Hydroxymethyl)-2-(methylthio)nicotinonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H8N2OS |
| Molecular Weight | 180.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Hydroxymethyl Standards
- 5-(Hydroxymethyl)-1H-benzo[d]imidazole-2(3H)-thione (CAS 92807-01-7)
- 1-Hydroxymethyl-4-oxoadamantane (CAS 110874-17-4)
- (2-(Hydroxymethyl)phenyl)propanoic acid (CAS 10172-25-5)
- N-((6-(Hydroxymethyl)pyridin-2-yl)methyl)acetamide (CAS 105243-75-2)
- methyl 3-(hydroxymethyl)-4-methylbenzoate (CAS 1427432-71-0)
- Methyl 2-(4-(hydroxymethyl)phenyl)acetate (CAS 155380-11-3)
- 3-(3-(Hydroxymethyl)phenyl)oxetan-3-ol (CAS 1644346-03-1)
- 1-[3-(hydroxymethyl)-4-methoxyphenyl]ethan-1-one (CAS 219539-06-7)
Recommended Standards
- 6-(Ethylthio)-7H-purine (CAS 5417-84-5)
- 6-(Thiophen-2-yl)-4,5-dihydropyridazin-3(2H)-one (CAS 52240-00-3)
- 6-((Methylthio)methyl)-9H-purine (CAS 3389-35-3)
- 6-Amino-2H-benzo[b][1,4]thiazin-3(4H)-one (CAS 21762-78-7)
- (R)-1-Morpholinopropan-2-amine (CAS 173336-87-3)
- 3-(3-Chlorophenyl)-4-cyanopropiophenone (CAS 898762-35-1)
- N-(2-aminophenyl)acrylamide (CAS 139039-23-9)
- 1-(Bromomethyl)-1-butylcyclopentane (CAS 1484064-37-0)
- 3-(1-(2-Ethylphenyl)-2,5-dimethyl-1h-pyrrol-3-yl)acrylic acid (CAS 924865-98-5)
- 1-(2,4,5-Trimethylphenyl)hexan-1-one (CAS 600653-41-6)
- 2-Acetoxy-2,4-difluorobenzophenone (CAS 890098-66-5)
- 1-(Bromomethyl)-4-(difluoromethyl)-2-fluorobenzene (CAS 2641114-14-7)
- 6-(Dimethylamino)quinolin-2(1H)-one (CAS 238756-51-9)
- Peptide 431 (CAS CATO-CPTD788431)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com