Glycopyrrolate Impurity 4 CAS 475468-09-8
| CAS No. | 475468-09-8 |
| Molecular Formula | C19H28NO3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Glycopyrrolate Impurity 4 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Glycopyrrolate Impurity 4 (CAS 475468-09-8), a pharmacopoeial impurity reference standard (molecular formula C19H28NO3Br, MW 398.34 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Glycopyrrolate Impurity 4 (C19H28NO3Br) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Glycopyrrolate Impurity 4 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H28NO3 Br |
| Molecular Weight | 398.34 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Glycopyrrolate Standards
- Glycopyrrolate Impurity 8 (CAS 104641-59-0)
- Glycopyrrolate Impurity 9 (CAS 104641-60-3)
- Glycopyrrolate Impurity 6 (CAS 1202407-99-5)
- Glycopyrrolate Impurity 6 (CAS 126497-27-6)
- Glycopyrrolate Impurity N13 (CAS 129784-11-8)
- Glycopyrrolate Impurity 12 (CAS 131237-81-5)
- Glycopyrrolate Impurity 5 (CAS 1404453-63-9)
- Glycopyrrolate Impurity 16 (CAS 201667-20-1)
Recommended Standards
- Roxatidine Impurity 29 (CAS CATO-C4X-121329)
- Loxoprofen Impurity 130 (CAS 261521-19-1)
- Cyclophosphamide EP Impurity F (CAS 1071-28-9)
- Pyridine, 4-chloro-3-isocyanato- (CAS 1250977-48-0)
- 5-(2,4-Dimethoxybenzyl)-5,6-dihydro-4H-pyrrolo[3,4-d]thiazole (CAS 1434128-55-8)
- Ethyl 5-amino-2,4-dichlorobenzoate (CAS 91151-73-4)
- Ethyl 2-(2,3-dihydrobenzo[b][1,4]dioxin-2-yl)thiazole-4-carboxylate (CAS 465514-25-4)
- 2-[1-(3-Chloro-2-cyanophenyl)-1H-pyrrol-2-yl]-N,N-diethyl-2-oxoacetamide (CAS 866010-47-1)
- 2-Chloropyridin-3-amine hydrochloride (CAS 94770-75-9)
- Gastric Inhibitory Polypeptide (1-30) amide (porcine) (CAS 134846-93-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com