Imatinib Impurity 36 CAS 475587-23-6
| CAS No. | 475587-23-6 |
| Molecular Formula | C16H13N5O2 |
| Molecular Weight | 307.31 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Imatinib Impurity 36 (C16H13N5O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 307.31 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Imatinib Impurity 36 (CAS 475587-23-6) is a certified pharmaceutical impurity reference standard with the molecular formula C16H13N5O2 and a molecular weight of 307.31 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H13N5O2 |
| Molecular Weight | 307.31 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 5 |
Related Imatinib Standards
- Imatinib Impurity 38 (CAS CATO-C4X-106838)
- Imatinib Impurity 39 (CAS 796738-71-1)
- Imatinib Impurity 49 (CAS CATO-C4X-106849)
- Imatinib Impurity 53 (CAS 152460-09-8)
- Imatinib Impurity 77 (CAS CATO-C4X-106877)
- Imatinib Impurity 8 (CAS 2410195-20-7)
- Imatinib Impurity 34 (CAS 765269-29-2)
- Imatinib Impurity 19 (CAS 3367-50-8)
Recommended Standards
- 3'-Deoxy-N-(1-oxopropyl)adenosine 77378-04-2 N6-Propionyl Cordycepin (CAS 77378-04-2)
- N'-isopropyl-N-(3-(trifluoromethyl)phenyl)nicotinimidamide (CAS 338420-59-0)
- N,3,5-Trimethyl-N-[4-(trifluoromethyl)phenyl]benzamide (CAS 338757-12-3)
- N,3,5-trimethyl-N-(3-(trifluoromethyl)phenyl)benzamide (CAS 338757-15-6)
- rac-Formoterol EP Impurity H (Mixture) (CAS 2514947-17-0)
- Selexipag Impurity 39 (CAS CATO-C4X-196139)
- Ixazomib Impurity 49 (CAS CATO-C4X-126749)
- 2-(4-(Aminomethyl)-5-(difluoromethyl)-3-hydroxypyridin-2-yl)acetic acid (CAS 1805066-25-4)
- 2-(2,3-Dimethoxyphenyl)-2-(1H-indol-3-yl)ethan-1-amine hydrochloride (CAS 1049752-42-2)
- 9-((2-Hydroxyethyl)amino)-9-oxononanoic acid (CAS 242132-61-2)
- tert-Butyl 4-amino-3-methoxybenzylcarbamate (CAS 401573-38-4)
- A5P604A12R 30272-08-3 Amineptine hydrochloride 7-((10,11-Dihydro-5H-dibenzo(a,d)cyclohepten-5-yl)amino)heptanoic acid hydrochloride Heptanoic acid, 7-((10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-yl)amino)-, hydrochloride EINECS 250-107-3 Maneon Survector Amineptine HCl UNII-A5P604A12R (CAS 30272-08-3)
- Methyl 2-(2-hydroxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetate (CAS 2870647-60-0)
- Semaglutide impurity 81 (CAS CATO-C4X-222681)
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