2-((4-(4-Chlorophenyl)-5-(4-methoxyphenyl)-4H-1,2,4-triazol-3-yl)thio)-N-(2,4-dichlorophenyl)acetamide CAS 476484-43-2
| CAS No. | 476484-43-2 |
| Molecular Formula | C23H17Cl3N4O2S |
| Molecular Weight | 519.83 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-((4-(4-Chlorophenyl)-5-(4-methoxyphenyl)-4H-1,2,4-triazol-3-yl)thio)-N-(2,4-dichlorophenyl)acetamide.
CATO supplies 2-((4-(4-Chlorophenyl)-5-(4-methoxyphenyl)-4H-1,2,4-triazol-3-yl)thio)-N-(2,4-dichlorophenyl)acetamide (CAS 476484-43-2), a certified reference material (molecular formula C23H17Cl3N4O2S, MW 519.83 g/mol) for analytical method development and quality control.
2-((4-(4-Chlorophenyl)-5-(4-methoxyphenyl)-4H-1,2,4-triazol-3-yl)thio)-N-(2,4-dichlorophenyl)acetamide (C23H17Cl3N4O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-((4-(4-Chlorophenyl)-5-(4-methoxyphenyl)-4H-1,2,4-triazol-3-yl)thio)-N-(2,4-dichlorophenyl)acetamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H17Cl3N4O2S |
| Molecular Weight | 519.83 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
- 2-((4-(4-Chlorophenyl)-5-(4-methoxyphenyl)-4H-1,2,4-triazol-3-yl)thio)-N-(2,6-dichlorophenyl)acetamide (CAS 476484-47-6)
- 2-((4-(4-Chlorophenyl)-5-(4-methoxyphenyl)-4H-1,2,4-triazol-3-yl)thio)-N-(3,4-dichlorophenyl)acetamide (CAS 476484-55-6)
- Bis(4-(4-chlorophenyl)-5-(propylthio)-4H-1,2,4-triazol-3-yl)methane (CAS 62575-62-6)
- 4-[(4-Chlorophenyl)sulfanyl]-6-{[(4-chlorophenyl)sulfanyl]methyl}-2-{[(4-fluorophenyl)methyl]sulfanyl}pyrimidine (CAS 341965-52-4)
- (5E)-3-(2-Chlorophenyl)-5-({2-[(4-chlorophenyl)sulfanyl]-5-nitrophenyl}methylidene)-2-sulfanylidene-1,3-thiazolidin-4-one (CAS 882073-17-8)
- (5E)-3-(2-Chlorophenyl)-5-({4-[(4-chlorophenyl)sulfanyl]-3-nitrophenyl}methylidene)-2-sulfanylidene-1,3-thiazolidin-4-one (CAS 298216-02-1)
- 2-((4-(2-Chlorophenyl)-6-(4-chlorophenyl)-3-cyanopyridin-2-yl)thio)-N-(4-methoxyphenyl)acetamide (CAS 337936-16-0)
- 4-(2-(2-(4-Chlorophenyl)-1H-indol-3-yl)hydrazinyl)-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide (CAS 88152-04-9)
Recommended Standards
- 4-((3,5-Bis(trifluoromethyl)phenoxy)methyl)-5-(chloromethyl)-2-(4-(trifluoromethyl)phenyl)thiazole (CAS 1365033-43-7)
- 3-[(1E)-1-{2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]hydrazin-1-ylidene}ethyl]-5-[3-(trifluoromethyl)phenyl]-3aH,4H,5H,6H,6aH-pyrrolo[3,4-d][1,2]oxazole-4,6-dione (CAS 339276-47-0)
- 5'-(4-Amino-3,5-diethylphenyl)-3,3'',5,5''-tetraethyl-[1,1':3',1''-terphenyl]-4,4''-diamine (CAS 2250216-97-6)
- 4-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}-6-hydroxy-1-[3-(trifluoromethyl)phenyl]-1,2-dihydropyrimidin-2-one (CAS 339012-76-9)
- (E)-3-(2-fluorophenyl)-2-methylacrylaldehyde (CAS 1375800-37-5)
- 2-(4,5-Dimethylthiophen-3-yl)ethanamine (CAS 933852-41-6)
- 1-(4-Chlorophenyl)-3-ethyl-1H-pyrazol-5-amine (CAS 1226186-68-0)
- 2-Methyltetrahydro-2H-pyran-2-carbohydrazide (CAS 1217862-65-1)
- 1-(1-Phenylethyl)-1H-pyrazol-3-amine (CAS 1240564-34-4)
- 2-Chloro-n-(propan-2-yl)-n-(2,2,2-trifluoroethyl)acetamide (CAS 1183184-66-8)
- (1R)-1-(Iodomethyl)-3,3-dimethyl-7-oxabicyclo[2.2.1]heptan-2-one (CAS 102304-99-4)
- 1-(2-Chloro-3-methylphenyl)hydrazine (CAS 60481-39-2)
- 5-Chloro-3-(chloromethyl)-2-fluoropyridine (CAS 1227606-17-8)
- (Leu31,Pro3?)-Neuropeptide Y (human, rat) trifluoroacetate salt (CAS 132699-73-1)
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